Efficacy and safety of proxalutamide (GT0918) in severe or critically ill patients with COVID-19: study protocol for a prospective, open-label, single-arm, single-center exploratory trial

被引：0
|
作者：
Dawei Yang
Minjie Ju
Hao Wang
Yichen Jia
Xiaodan Wang
Hao Fang
Jia Fan
机构：
[1] Zhongshan Hospital Fudan University,Department of Pulmonary and Critical Care Medicine
[2] Zhongshan Hospital (Xiamen),Department of Pulmonary and Critical Care Medicine
[3] Fudan University,Department of Critical Care Medicine
[4] Shanghai Engineer & Technology Research Center of Internet of Things for Respiratory Medicine,Department of Thoracic Surgery
[5] Zhongshan Hospital Fudan University,Department of Urology
[6] Zhongshan Hospital Fudan University,Department of Anesthesiology
[7] Zhongshan Hospital Fudan University,Department of Anesthesiology
[8] Zhongshan Hospital Fudan University,Department of Liver Surgery and Transplantation
[9] Minhang Hospital,Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences
[10] Fudan University,undefined
[11] Liver Cancer Institute,undefined
[12] Zhongshan Hospital,undefined
[13] Fudan University,undefined
[14] Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education，Fudan University,undefined
[15] Fudan University,undefined
来源：
BMC Pharmacology and Toxicology | / 24卷
关键词：
COVID-19; Critical ill COVID-19; Proxalutamide; Severe COVID-19;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Exploring Paxlovid Efficacy in COVID-19 Patients with MAFLD: Insights from a Single-Center Prospective Cohort Study
    Buchynskyi, Mykhailo
    Oksenych, Valentyn
    Kamyshna, Iryna
    Kamyshnyi, Oleksandr
    VIRUSES-BASEL, 2024, 16 (01):
  • [32] Clinical characteristics and outcomes of critically ill COVID-19 patients in Tokyo: a single-center observational study from the first wave
    Aya Banno
    Toru Hifumi
    Hiroshi Okamoto
    Minori Masaki
    Koichiro Seki
    Shutaro Isokawa
    Norio Otani
    Kuniyoshi Hayashi
    Shinichi Ishimatsu
    BMC Infectious Diseases, 21
  • [33] Clinical characteristics and outcomes of critically ill COVID-19 patients in Tokyo: a single-center observational study from the first wave
    Banno, Aya
    Hifumi, Toru
    Okamoto, Hiroshi
    Masaki, Minori
    Seki, Koichiro
    Isokawa, Shutaro
    Otani, Norio
    Hayashi, Kuniyoshi
    Ishimatsu, Shinichi
    BMC INFECTIOUS DISEASES, 2021, 21 (01)
  • [34] Efficacy and Safety of Inhaled Ciclesonide in Treating Patients With Asymptomatic or Mild COVID-19 in the RACCO Trial: Protocol for a Multicenter, Open-label, Randomized Controlled Trial
    Terada-Hirashima, Junko
    Suzuki, Manabu
    Uemura, Yukari
    Hojo, Masayuki
    Mikami, Ayako
    Sugiura, Wataru
    Ohmagari, Norio
    Sugiyama, Haruhito
    JMIR RESEARCH PROTOCOLS, 2020, 9 (12):
  • [35] Semiquantitative lung ultrasound scores in the evaluation and follow-up of critically ill patients with COVID-19: a single-center study
    Deng, Qing
    Zhang, Yao
    Wang, Hao
    Chen, Liao
    Yang, Zhaohui
    Peng, Zhoufeng
    Liu, Ya
    Feng, Chuangli
    Huang, Xin
    Jiang, Nan
    Wang, Yijia
    Guo, Juan
    Sun, Bin
    Zhou, Qing
    ACADEMIC RADIOLOGY, 2020, 27 (10) : 1363 - 1372
  • [36] Safety and efficacy of fluvoxamine in COVID-19 ICU patients: An open label, prospective cohort trial with matched controls
    Calusic, Martina
    Marcec, Robert
    Luksa, Lea
    Jurkovic, Ivan
    Kovac, Natasa
    Mihaljevic, Slobodan
    Likic, Robert
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2022, 88 (05) : 2065 - 2073
  • [37] Immunogenicity and safety of single booster dose of KD-414 inactivated COVID-19 vaccine in adults: An open-label, single-center, non-randomized, controlled study in Japan
    Terada-Hirashima, Junko
    Takamatsu, Yuki
    Shimizu, Yosuke
    Uemura, Yukari
    Takeuchi, Junko S. S.
    Tomita, Noriko
    Matsuda, Kouki
    Maeda, Kenji
    Yamamoto, Shohei
    Fukunaga, Ami
    Ohmagari, Norio
    Mikami, Ayako
    Sonoda, Kengo
    Ujiie, Mugen
    Mitsuya, Hiroaki
    Sugiura, Wataru
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2023, 19 (01)
  • [38] Risk factors for mortality in critically ill patients with COVID-19 in Huanggang, China: A single-center multivariate pattern analysis
    Chen, Yinyin
    Linli, Zeqiang
    Lei, Yuting
    Yang, Yiya
    Liu, Zhipeng
    Xia, Youchun
    Liang, Yumei
    Zhu, Huabo
    Guo, Shuixia
    JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (04) : 2046 - 2055
  • [39] The İmportance of hematological parameters in the prognosis of patients with severe COVID-19, A single-center retrospective study
    Gozukucuk, R.
    Kilic, H. H.
    Uyanik, B. S.
    Cakiroglu, B.
    NIGERIAN JOURNAL OF CLINICAL PRACTICE, 2023, 26 (09) : 1297 - 1302
  • [40] Clinical Characteristics of Patients with Severe and Critical COVID-19 in Wuhan: A Single-Center, Retrospective Study
    Chen, Zhaohui
    Hu, Junyi
    Liu, Lilong
    Zhang, Youpeng
    Liu, Dandan
    Xiong, Ming
    Zhao, Yi
    Chen, Ke
    Wang, Yu-Mei
    INFECTIOUS DISEASES AND THERAPY, 2021, 10 (01) : 421 - 438
12345