Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line

[1] Parkin DM(2001)Estimating the world cancer burden:Globoscan 2000. Int J Cancer 94 153-6

[2] Bray F(2000)Role of herbal compounds (PC-SPES) in hormone-refractory prostate cancer: two case reports. J Altern Complement Med 6 449-51

[3] Ferlay J(2000)Chinese herbal mixture PC SPES in treatment of prostate cancer (review). Int J Oncol 17 729-36

[4] Pisani P(2005)Novel mechanism of inhibition of nuclear factor-kappa B DNA-bindng activity by diterpenoids isolated from Isodon rubescens. Mol Pharmacol 68 286-97

[5] de la Taille A(2000)A new diterpene glycoside from Rabdosia rubescens. Chem Pharm Bull (Tokyo) 48 148-9

[6] Hayek OR(2005)Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways. Mol Cancer Ther 4 578-86

[7] Burchardt M(2005)Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the Chinese herb Rabdosia rubescens. Biochem Biophys Res Commun 337 224-31

[8] Burchardt T(2006)Oridonin inhibits cell growth by induction of apoptosis on human hepa-tocellular carcinoma BEL-7402 cells. Hepatol Res 35 104-10

[9] Katz AE(2004)Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. J Int Med Res 32 617-25

[10] Darzynkiewicz Z(2007)Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells. Cancer Biol Ther 6 261-8

[1] Parkin DM(2001)Estimating the world cancer burden:Globoscan 2000. Int J Cancer 94 153-6

[2] Bray F(2000)Role of herbal compounds (PC-SPES) in hormone-refractory prostate cancer: two case reports. J Altern Complement Med 6 449-51

[3] Ferlay J(2000)Chinese herbal mixture PC SPES in treatment of prostate cancer (review). Int J Oncol 17 729-36

[4] Pisani P(2005)Novel mechanism of inhibition of nuclear factor-kappa B DNA-bindng activity by diterpenoids isolated from Isodon rubescens. Mol Pharmacol 68 286-97

[5] de la Taille A(2000)A new diterpene glycoside from Rabdosia rubescens. Chem Pharm Bull (Tokyo) 48 148-9

[6] Hayek OR(2005)Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways. Mol Cancer Ther 4 578-86

[7] Burchardt M(2005)Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the Chinese herb Rabdosia rubescens. Biochem Biophys Res Commun 337 224-31

[8] Burchardt T(2006)Oridonin inhibits cell growth by induction of apoptosis on human hepa-tocellular carcinoma BEL-7402 cells. Hepatol Res 35 104-10

[9] Katz AE(2004)Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. J Int Med Res 32 617-25

[10] Darzynkiewicz Z(2007)Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells. Cancer Biol Ther 6 261-8