Effects of single episodes of severe stress on the behavior of male and female CBA/Lac and C57BL/6J mice

被引：6

作者：

Avgustinovich D.F. ^{[1
]}

Kovalenko I.L. ^{[1
]}

Koryakina L.A. ^{[1
]}

机构：

[1] Social Behavior Neurogenetics Sector, Institute of Cytology and Genetics, Russian Academy of Sciences, 630090 Novosibirsk

来源：

Neuroscience and Behavioral Physiology | 2007年 / 37卷 / 7期

关键词：

Behavior; CBA/Lac and C57BL/6J mice; Females; Forced swimming; Males; Openfield;

D O I：

10.1007/s11055-007-0075-7

中图分类号：

学科分类号：

摘要：

Experiments were performed to compare the behavior of male and female mice of the inbred strains CBA/Lac and C57BL/6J in the open field test after single episodes of severe stress imposed by forced swimming. Testing was performed 2 h (first test) and one day (second test) after stress. Control animals were intact males and females of these strains, and were also tested in the open field on two sequential days. Both male and female CBA/Lac mice showed increases in the latent period of excursions from the center of the field 2 h after stress. This change persisted to the second test in female CBA/Lac mice. In female C57BL/6J mice, there were changes in four of seven behavioral measures 2 h after stress, though at one day their behavior was as in control individuals. Stress had virtually no effect in males of this strain, only increasing the number of grooming acts in the first test. In addition, detailed analysis of the effects of repeat testing in control and stressed individuals of these mouse strains also revealed interstrain and gender-related differences in the effects of stress. The possible existence of increased basal (trait) and situational (state) anxiety in female C57BL/6J and CBA/Lac mice respectively is discussed. © Springer Science+Business Media, Inc. 2007.

引用

页码：731 / 737

页数：6

共 31 条

[1]

Avgustinovich D.F., Kovalenko I.L., Prolonged individual isolation of C57BL/6J mice induces anxiety, Ros. Fiziol. Zh. Im. I. M. Sechenova, 90, 3, pp. 351-360, (2004)

[2]

Avgustinovich D.F., Kovalenko I.L., Formation of behavioral pathology in female C57BL/6J mice in conditions of prolonged psychoemotional tension, Ros. Fiziol. Zh. Im. I. M. Sechenova, 90, 11, pp. 1324-1336, (2004)

[3]

Avgustinovich D.F., Lyudvina N.A., Dolgov V.V., Alekseenko O.V., Effects of prolonged restriction stress on the behavior of female mice of the inbred strains C57BL/6J and CBA/Lac: Dispersion and cluster analysis, Ros. Fiziol. Zh. Im. I. M. Sechenova, 87, 9, pp. 1268-1282, (2001)

[4]

Kaluev A.V., Grooming and Stress, (2002)

[5]

Avgustinovich D.F., Lipina T.V., Bondar N.P., Alekseyenko O.V., Kudryavtseva N.N., Features of genetically defined anxiety in mice, Behav. Genet., 30, 2, pp. 101-109, (2000)

[6]

Ammassari-Teule M., Fagioli S., Rossi-Arnaud C., Radial maze performance and open-field behaviours in aged C57BL/6 mice: Further evidence for preserved cognitive abilities during senescence, Physiol. Behav., 55, 2, pp. 341-345, (1994)

[7]

Archer J., Rodent sex differences in emotional and related behaviour, Behav. Biol., 14, pp. 451-479, (1975)

[8]

Belzung C., Griebel G., Measuring normal and pathological anxiety-like behaviour in mice: A review, Behav. Brain Res., 125, pp. 141-149, (2001)

[9]

Choleris E., Thomas A.W., Kavaliers M., Prato F.S., A detailed ethological analysis of the mouse open field test: Effects of diazepam, chlordiazepoxide and extremely low frequency pulsed magnetic field, Neurosci. Biobehav. Rev., 25, pp. 235-260, (2001)

[10]

Crowley J.N., Belknap J.K., Collins A., Crabbe J.C., Frankel W., Henderson N., Hitzemann R.J., Maxson S.C., Miner L.L., Silva A.J., Wehner J.M., Wynshaw-Boris Paylor A.R., Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies, Psychopharmacology, 132, 2, pp. 107-124, (1997)

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