Is it time to increase the frequency of use of high-frequency oscillatory ventilation?

被引：0
作者：
Jeffrey M Singh
Niall D Ferguson
机构：
[1] University Health Network,Lecturer, Interdepartmental Division of Critical Care Medicine, and Department of Medicine, Division of Respirology
[2] University of Toronto,Assistant Professor, Interdepartmental Division of Critical Care Medicine, and Department of Medicine, Division of Respirology
[3] University Health Network,undefined
[4] University of Toronto,undefined
来源：
Critical Care | / 9卷
关键词：
Acute Respiratory Distress Syndrome; Oxygenation Index; Acute Respiratory Distress Syndrome Patient; Conventional Mechanical Ventilation; Conventional Ventilation;
D O I：
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学科分类号：
摘要：
In this issue of Critical Care, Bollen and colleagues present the results of a multicentre randomised controlled trial, comparing high-frequency oscillatory ventilation with conventional ventilation as the primary ventilation mode for adults with acute respiratory distress syndrome. The study was stopped early after recruiting only 61 patients because of declining enrolment, and although no differences were detected in any primary or secondary endpoint, this trial only had sufficient power to detect extreme differences in outcomes between groups. This editorial attempts to put these results in context with previous work and highlights challenges to be addressed in future studies.
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