Beta-blockers and amiodarone for the primary prevention of sudden cardiac death

被引：3
|
作者：
Frankenberger O. [1 ]
Steinber J.S. [1 ]
机构：
[1] Department of Medicine, St Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025
来源：
Current Cardiology Reports | 1999年 / 1卷 / 4期
关键词：
Amiodarone; Metoprolol; Sudden Cardiac Death; Carvedilol; Antiarrhythmic Drug;
D O I：
10.1007/s11886-999-0050-8
中图分类号：
学科分类号：
摘要：
Sudden cardiac death remains a major public health care problem, generally occurring in patients with ventricular dysfunction. Beta-blockers, already of proven benefit for patients after myocardial infarction, have recently been shown to improve functional status and mortality outcomes in patients with heart failure. Amiodarone, a potent antiarrhythmic drug, was recently studied in a number of randomized clinical trials involving patients with heart failure and patients after myocardial infarction. Routine use of amiodarone cannot be recommended in these patient groups, but serious adverse outcomes were not observed. When antiarrhythmic drug therapy is required, amiodarone is the drug of choice for patients with structural heart disease. Copyright © 1999 by Current Science Inc.
引用
收藏
页码：274 / 281
页数：7
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