German guidelines for the sequential medical treatment of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs

被引：0
作者：
Katinka Albrecht
Klaus Krüger
Jürgen Wollenhaupt
Rieke Alten
Marina Backhaus
Christoph Baerwald
Wolfgang Bolten
Jürgen Braun
Harald Burkhardt
Gerd R. Burmester
Markus Gaubitz
Angela Gause
Erika Gromnica-Ihle
Herbert Kellner
Jens Kuipers
Andreas Krause
Hans-Martin Lorenz
Bernhard Manger
Hubert Nüßlein
Hans-Georg Pott
Andrea Rubbert-Roth
Matthias Schneider
Christof Specker
Hendrik Schulze-Koops
Hans-Peter Tony
Siegfried Wassenberg
Ulf Müller-Ladner
机构：
[1] German Society of Rheumatology,Department of Internal Medicine, Rheumatology, Schlosspark
[2] Centre of Rheumatology,Clinic
[3] Rheumatologikum,Department of Rheumatology and Clinical Immunology
[4] Schoen Hospital,Department of Rheumatology and Gerontology
[5] University Medicine Berlin,Department of Internal Medicine and Rheumatology
[6] Charité University Medicine Berlin,Centre of Rheumatology Ruhr
[7] Free University and Humboldt University,Department of Rheumatology
[8] University of Leipzig,Interdisciplinary Diagnostic and Therapy
[9] Klaus Miehlke Hospital,Department of Internal Rheumatology
[10] St. Josef Hospital,Department of Rheumatology
[11] Johann Wolfgang Goethe University,Division of Rheumatology, Department of Medicine V
[12] WWU,Department of Rheumatology
[13] Centre of Rheumatology and Autoimmunology,Department of Immunology and Rheumatology
[14] German League Against Rheumatism,Department of Rheumatology
[15] Practice for Rheumatology and Gastroenterology and Head of the Department of Rheumatology Hospital Neuwittelsbach,Department of Rheumatology and Clinical Immunology
[16] Red Cross Hospital,Division of Rheumatology and Clinical Immunology, Med. Klinik und Poliklinik IV
[17] Immanuel Hospital,Department of Rheumatology and Clinical Immunology
[18] Berlin-Buch,Department of Rheumatology and Clinical Immunology
[19] University of Heidelberg,undefined
[20] University of Erlangen,undefined
[21] Practice of Internal Rheumatology,undefined
[22] Practice of Rheumatology,undefined
[23] Physical Therapy and Clinical Immunology,undefined
[24] University of Cologne,undefined
[25] Heinrich-Heine-University,undefined
[26] Kliniken Essen Süd,undefined
[27] LMU München,undefined
[28] University of Wurzburg,undefined
[29] Evangelisches Fachkrankenhaus Ratingen,undefined
[30] Rheumatologie,undefined
[31] Justus-Liebig University,undefined
[32] Giessen,undefined
[33] Kerckhoff Klinik,undefined
来源：
Rheumatology International | 2014年 / 34卷
关键词：
Rheumatoid arthritis; Clinical practice guideline; Disease-modifying antirheumatic drugs; Glucocorticoids; Biologic agents;
D O I：
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学科分类号：
摘要：
The German Society of Rheumatology approved new German guidelines for the sequential medical treatment of rheumatoid arthritis (RA) based on the European League Against Rheumatism (EULAR) recommendations for the management of RA published in 2010. An update of the EULAR systematic literature research was performed in Medline, Embase, and Cochrane databases. Meta-analyses, controlled trials, cohort studies, and registry data addressing traditional and biologic disease-modifying antirheumatic drugs, glucocorticoids, and treatment strategies published between January 2009 and August 2011 were included. Two reviewers independently evaluated and compared the additional data that had been published after the time limit set by the EULAR recommendations. A national guideline working group developed an adapted set of recommendations. The new German guidelines were accepted by vote using an informal Delphi approach. Twelve recommendations and the resulting updated treatment algorithm were developed and approved as a practical orientation for rheumatologists. These recommendations are based on a successive treatment with traditional and biologic disease-modifying drugs depending on the individual progress of the disease and distinct patient characteristics. The German guidelines have been developed on the basis of the internationally well-recognized EULAR recommendations. In addition, more recent evidence from a systematic literature research was considered. They have been developed and approved by a group of national experts aiming at guidance for rheumatologists to reach best medical practice.
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