Cerebral small vessel disease increases risk for epilepsy: a Mendelian randomization study

[1] Pantoni LM(2010)Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges Lancet Neurol 9 689-701

[2] Wardlaw JM(2013)Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration Lancet Neurol 12 822-838

[3] Smith EE(2020)Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants Nat Commun 11 2175-27

[4] Biessels GJ(2023)The global burden of cerebral small vessel disease in low- and middle-income countries: a systematic review and meta-analysis Int J Stroke 18 15-482

[5] Persyn E(2014)ILAE official report: a practical clinical definition of epilepsy Epilepsia 55 475-e995

[6] Hanscombe KB(2019)Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy Neurology 92 e988-1089

[7] Howson J(2021)Relationship of white matter hyperintensities with clinical features of seizures in patients with epilepsy Arq Neuropsiquiatr 79 1084-194

[8] Lam B(1988)Clinically unsuspected cerebral infarction revealed by computed tomography scanning in late onset epilepsy Epilepsia 29 190-696

[9] Cai Y(2019)Small vessel disease: mechanisms and clinical implications Lancet Neurol 18 684-129

[10] Akinyemi R(2018)Review: animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis Neuropathol Appl Neurobiol 44 112-216

[1] Pantoni LM(2010)Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges Lancet Neurol 9 689-701

[2] Wardlaw JM(2013)Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration Lancet Neurol 12 822-838

[3] Smith EE(2020)Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants Nat Commun 11 2175-27

[4] Biessels GJ(2023)The global burden of cerebral small vessel disease in low- and middle-income countries: a systematic review and meta-analysis Int J Stroke 18 15-482

[5] Persyn E(2014)ILAE official report: a practical clinical definition of epilepsy Epilepsia 55 475-e995

[6] Hanscombe KB(2019)Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy Neurology 92 e988-1089

[7] Howson J(2021)Relationship of white matter hyperintensities with clinical features of seizures in patients with epilepsy Arq Neuropsiquiatr 79 1084-194

[8] Lam B(1988)Clinically unsuspected cerebral infarction revealed by computed tomography scanning in late onset epilepsy Epilepsia 29 190-696

[9] Cai Y(2019)Small vessel disease: mechanisms and clinical implications Lancet Neurol 18 684-129

[10] Akinyemi R(2018)Review: animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis Neuropathol Appl Neurobiol 44 112-216