Drug-Induced Nail Abnormalities

被引：0
作者：
Bianca Maria Piraccini
Matilde Iorizzo
Antonella Tosti
机构：
[1] University of Bologna,Department of Dermatology
来源：
American Journal of Clinical Dermatology | 2003年 / 4卷
关键词：
Retinoid; Indinavir; Nail Plate; Pyogenic Granuloma; Paronychia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This article reviews the different nail symptoms produced by drugs. Drug-induced nail abnormalities may result from toxicity to the matrix, the nail bed or the periungual tissues. The most common symptoms include Beau’s lines/onychomadesis, melanonychia, onycholysis, and periungual pyogenic granulomas. Nail changes usually affect several nails and in most cases are asymptomatic. Drugs that most frequently produce nail abnormalities include retinoids, indinavir, and cancer chemotherapeutic agents. In this article, we also include nail adverse effects as a result of radiotherapy since they are commonly observed in clinical practice.
引用
收藏
页码：31 / 37
页数：6
相关论文
共 42 条
  • [1] Piraccini BM(1999)Drug-induced nail disorders: incidence, management and prognosis Drug Saf 21 187-201
  • [2] Tosti A(1984)Nail changes secondary to systemic drugs or ingestans J Am Acad Dermatol 10 250-258
  • [3] Daniel CR(1990)Retinoids and the nail J Dermatol Treat 1 151-154
  • [4] Scher RK(1989)Longitudinal melanonychia: diagnosis and management J Am Acad Dermatol 21 1165-1175
  • [5] Baran R(2000)Subungual abscess: an ungual side-effect related to docetaxel therapy Br J Dermatol 43 445-473
  • [6] Baran R(2000)Onycholysis as a complication of systemic chemotherapy: report of five cases associated with prolonged weekly paclitaxel therapy and review of the literature Cancer 88 2367-2371
  • [7] Kechijian P(1997)Subungual hematoma in a patient treated with an oral anticoagulant (warfarin sodium) Eur J Dermatol 7 395-396
  • [8] Vanhooteghem O(1986)Etretinate and the nails (study of 130 cases): possible mechanisms of some side effects Clin Exp Dermatol 11 148-152
  • [9] Richert B(1998)Paronychia and pyogenic granuloma of the great toes in patients with indinavir N Engl J Med 338 1776-1777
  • [10] Vindevoghel A(2000)Cutaneous side effects induced by indinavir Eur J Dermatol 10 292-296
12345