Synthesis of fluorine-containing benzimidazole derivatives

被引：0
|
作者：
T. P. Vasilyeva
N. M. Karimova
Yu. V. Slavich
机构：
[1] Russian Academy of Sciences,A. N. Nesmeyanov Institute of Organoelement Compounds
来源：
Russian Chemical Bulletin | 2010年 / 59卷
关键词：
Key words; 2-(1,2,2,2-tetrafluoroethyl)-1; -benzimidazole; 2-[(fluoro)trifluoromethoxy-methyl]-1; -benzimidazole; 2-difluoromethyl-1; -benzimidazole; 6- or 5-substituted 2-(1,2,2,2-tetrafluoroethyl)- and 2-[(fluoro)trifluoromethoxymethyl]-1; -benzimidazoles, ; -phenylenediamine; 3,4-diaminotoluene; 1,2-diamino-4-chlorobenzene; hexafluoropropene; perfluoro(methyl vinyl ether); heterocyclization; silylation;
D O I：
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学科分类号：
摘要：
Various fluorine-containing benzimidazoles were obtained by the reaction of o-phenylene-diamine, 3,4-diaminotoluene, and 1,2-diamino-4-chlorobenzene with hexafluoropropene or perfluoro(methyl vinyl ether) in DMF. A new efficient method of synthesis of 2-(1,2,2,2-tet-rafluoroethyl)benzimidazole by the reaction of o-phenylenediamine with hexafluoropropene in the presence of diethylamine or dimethylamine in ethyl acetate is developed.
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页码：186 / 191
页数：5
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