Huntington's disease: A decade beyond gene discovery

被引：7
作者：
Penelope Hogarth
机构：
[1] Oregon Health and Science University, Portland, OR 97239-3098
来源：
Current Neurology and Neuroscience Reports | 2003年 / 3卷 / 4期
关键词：
Huntington Disease; Riluzole; Mutant Huntingtin; Remacemide; Total Functional Capacity;
D O I：
10.1007/s11910-003-0003-3
中图分类号：
学科分类号：
摘要：
Huntington's disease is a dominantly inherited neurodegenerative disease that causes a progressive movement disorder, cognitive decline, and varying degrees of psychiatric dysfunction. The identification of the mutant gene in 1993 paved the way for a decade of basic research. The resultant advances in our understanding of the pathogenesis of the disorder are moving us toward rational therapies to slow the progression and delay the onset of the illness. Copyright © 2003 by Current Science Inc.
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收藏
页码：279 / 284
页数：5
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