Optical Imaging: Future Tool in Detection of Pre-cancerous and Cancerous Lesions of Cervix and Its Comparison to Colposcopy

被引：5

作者：

Pandey K. ^{[1
]}

Bhagoliwal A. ^{[2
]}

Jain S. ^{[1
]}

机构：

[1] Department of Obstetrics and Gynecology, G.S.V.M. Medical College, Flat No. 104, Narayandeep Appt., 7/81, Tilaknagar, Kanpur, 208002, UP

[2] Department of SPM, G.S.V.M. Medical College, Kanpur, UP

来源：

The Journal of Obstetrics and Gynecology of India | 2015年 / 65卷 / 3期

关键词：

Cancer cervix; Colposcopy; Depolarization power; Optical imaging;

D O I：

10.1007/s13224-014-0511-x

中图分类号：

学科分类号：

摘要：

Objectives: To study the diagnostic potential of optical imaging and its comparison with colposcopy, in detecting early cervical dysplasia Methods: The study was conducted on 200 patients attending the outdoor of UISE maternity hospital with symptoms suspicious of cervical lesions. All patients were subjected to colposcopy, followed by histo-pathological examination. Out of all HPE, 18 samples each from normal and dysplastic histology were sent to IIT Physics lab, Kanpur for optical imaging. Statistical analysis was done using sensitivity, specificity, PPV, and NPV. Chi square test was applied to calculate p value Results: In optical imaging, depolarization images had shown significant changes in the epithelium region of the dysplastic tissue as compared to normal one. It is found that the mean value of depolarization power for normal cervix tissues is less than 0.32, while for dysplastic tissues it is greater than 0.32 Conclusion: Optical imaging is fast, non-invasive tool with high sensitivity and specificity, comparable to colposcopy (sensitivity 88.9 vs 100 %, specificity 83.3 vs 86.6 %) and thus is useful in both for screening and diagnosis of cervical dysplasia © 2014, Federation of Obstetric & Gynecological Societies of India.

引用

页码：176 / 180

页数：4

共 8 条

[1]

Arbyn M., Et al., Pooled analysis of the accuracy of five cervical cancer screening tests assessed in eleven studies in Africa and India, Int J Cancer, 123, pp. 153-160, (2008)

[2]

Singh V., Seghal A., Luthra U.K., Screening for cervical cancer by direct inspection, Br Med J, 304, pp. 534-535, (1992)

[3]

Singh A., Arthur B., Agarwal B., LEEP versus cryotherapy in CIN, J Obstetrics Gynecol India, 61, 4, pp. 431-435, (2011)

[4]

Robert A.S., Vilma C., Durado B., Debbie S., Mona S., Otis W.B., A review of current American cancer society guidelines and issues in cancer screening, Cancer J Clin, 61, pp. 8-30, (2011)

[5]

Pandey K., Bhagoliwal A., Cancer cervix—need for mass surveillance program specially rural areas, J Obstetrics Gynecol India, 55, pp. 436-439, (2005)

[6]

Thekkek N., Richards Kortum R., Optical imaging for cervical cancer detection: solution for a continuing global programme, Nat Rev Cancer, 8, pp. 725-731, (2008)

[7]

Ian J.E., Colposcopic appearances of CIN, J Gynecologic Oncol, 10, pp. 69-76, (2005)

[8]

Mojgan K.Z., Fariba B., Zohre K., Soraya T., Hamid R.S., Zohre C., Value of colposcopy in the early diagnosis of cervical cancer in patients with abnormal pap smears at Shahid Sadoughi Hospital, Yazd, Asian Pac J Cancer Prev, 12, pp. 3439-3441, (2011)

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