Peritoneal dialysis for chronic renal failure in a patient with methylmalonic acidaemia

被引：0
作者：
Bemigho Etuwewe
Caroline A. Jones
Shipra Mathur
Katherine P. Wright
Andrew A. M. Morris
机构：
[1] Royal Liverpool Children’s Hospital,Department of Nephrology
[2] Royal Liverpool Children’s Hospital,Department of Biochemistry
[3] Royal Manchester Children’s Hospital,Willink Biochemical Genetics Unit
来源：
Pediatric Nephrology | 2009年 / 24卷
关键词：
Chronic renal failure; End stage renal failure; Methylmalonic acidaemia; MMA clearance; Peritoneal dialysis;
D O I：
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摘要：
Chronic renal failure is a common complication of methylmalonic acidaemia (MMA). It is usually managed with haemodialysis and renal transplantation. We report the use of continuous cycling peritoneal dialysis (CCPD) for 20 months in a paediatric patient with chronic renal failure due to MMA. This procedure resulted in the elimination of 950 μmol methylmalonate (MM) per day and a fall in the plasma MM concentration from 3.9 to 0.74 mmol/l. As a result of this treatment, the frequency at which this patient was hospitalised was markedly reduced prior to a successful renal transplantation.
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页码：1085 / 1087
页数：2
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