Atypical thyrotropin-secreting pituitary microadenoma revealed by severe osteoporosis in a young man

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作者
Alexis de Rougemont
Marie-Gabrielle Mourot
Jean-Paul Riou
机构
[1] Hôpital E. Herriot,Service d’Endocrinologie
[2] Hôpital du Bocage,Diabétologie
[3] Hôpital du Bocage,Pôle Technique de Biologie
[4] Hôpital Edouard Herriot,Service d’Imagerie Médicale
来源
Journal of Bone and Mineral Metabolism | 2009年 / 27卷
关键词
Osteoporosis; TSH; α-Subunits; Pituitary adenoma; Hyperthyroidism;
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摘要
For 10 years, a young man was followed for a severe osteoporosis associated with a considerable reduction in height and a massive weight loss. The constant increase of signs of tissue impregnation with thyroid hormones and the molar ratios of α-TSH suggested an inappropriate secretion of thyrotropin. Magnetic resonance imaging finally revealed a thyrotropic microadenoma of the pituitary gland. This case gives some new additional information on thyrotropin-induced osteoporosis. To our knowledge such a case has never been reported in the literature.
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