Changes in iron, calcium, magnesium, copper, and zinc levels in different tissues of riboflavin-deficient rats

被引：0
作者：
HuiJun Chen
Mieko Kimura
Yoshinori Itokawa
机构：
[1] Kyoto University,Department of Social Medicine, Graduate School of Medicine
来源：
Biological Trace Element Research | 1997年 / 56卷
关键词：
Riboflavin deficiency; iron; calcium; magnesium; copper; zinc;
D O I：
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学科分类号：
摘要：
To clarify the changes of mineral levels in different tissues of riboflavin-deficient rats, Wistar rats were separated into three groups. One group was fed a diet ad libitum that was deficient in riboflavin. The other two were fed either the complete diet that was weight-matched to the riboflavin-deficient group or fed a complete diet ad libitum. In riboflavin-deficient rats, the hemoglobin concentration and riboflavin contents of blood, liver, and kidney were significantly decreased, compared with weight-matched and ad libitum-fed controls. The mineral concentrations of tissues are summarized as follows: The iron (Fe) concentration in the heart, liver, and spleen was decreased in the riboflavin-deficient group compared with the other groups. Calcium (Ca) and magnesium (Mg) concentrations in tibia were decreased in the riboflavin-deficient group compared with the other two groups. Copper (Cu) concentration was increased in the heart and liver when the riboflavin-deficient group was compared with the other groups. Zinc (Zn) concentration was increased in tibia when the riboflavin-deficient group was compared with the other groups.
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页码：311 / 319
页数：8
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