Self-perception and Experiential Schemata in the Addicted Brain

被引：0
作者：
Rex Cannon
Joel Lubar
Debora Baldwin
机构：
[1] University of Tennessee at Knoxville,Brain Research and Neuropsychology Laboratory, Department of Psychology
来源：
Applied Psychophysiology and Biofeedback | 2008年 / 33卷
关键词：
Addiction; Self-perception; Neurophysiological assessment; EEG biofeedback; LORETA;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study investigated neurophysiological differences between recovering substance abusers (RSA) and controls while electroencephalogram (EEG) was continuously recorded during completion of a new assessment instrument. The participants consisted of 56 total subjects; 28 RSA and 28 non-clinical controls (C). The participants completed the self-perception and experiential schemata assessment (SPESA) and source localization was compared utilizing standardized low-resolution electromagnetic tomography (sLORETA). The data show significant differences between groups during both the assessment condition and baselines. A pattern of alpha activity as estimated by sLORETA was shown in the right amygdala, uncus, hippocampus, BA37, insular cortex and orbitofrontal regions during the SPESA condition. This activity possibly reflects a circuit related to negative perceptions of self formed in specific neural pathways. These pathways may be responsive to the alpha activity induced by many substances by bringing the brain into synchrony if only for a short time. In effect this may represent the euphoria described by substance abusers.
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  • [1] Abrahams S(2003)Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses Human Brain Mapping 20 29-40
  • [2] Goldstein LH(2004)Neurobiologic processes in drug reward and addiction Harvard Review of Psychiatry 12 305-320
  • [3] Simmons A(2006)Sex differences in medial and lateral orbitofrontal cortex hypoperfusion in cocaine-dependent men and women Gender Medicine: Official Journal of the Partnership for Gender-Specific Medicine at Columbia University 3 206-222
  • [4] Brammer MJ(2005)Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction Proceedings of the National Academy of Sciences of the United States of America 102 11533-11538
  • [5] Williams SC(2007)Addiction severity index recent and lifetime summary indexes based om nonparametric item response theory models Psychological Assessment 19 119-132
  • [6] Giampietro VP(2002)Ageing of the brain Mechanisms of Ageing and Development 123 811-817
  • [7] Adinoff B(2005)Instrumental learning, but not performance, requires dopamine D1-receptor activation in the amygdala Neuroscience 135 335-345
  • [8] Adinoff B(1977)Self-efficacy: Toward a unifying theory of behavioral change Psychological Review 84 191-215
  • [9] Williams M(2002)Decision-making and addiction (part I): Impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences Neuropsychologia 40 1675-1689
  • [10] Best S(2008)Reduced posterior mesofrontal cortex activation by risky rewards in substance-dependent males Drug and Alcohol Dependence 95 115-128
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