Tracing lineages to uncover neuronal identity

被引:0
|
作者
Lia Panman
Thomas Perlmann
机构
[1] Ludwig Institute for Cancer Research Ltd,Department of Cell and Molecular Biology
[2] Karolinska Institute,undefined
来源
BMC Biology | / 9卷
关键词
MPTP; Ventral Tegmental Area; Neuron Progenitor; Postmitotic Neuron; Neuron Subtype;
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学科分类号
摘要
Many previous studies have focused on understanding how midbrain dopamine neurons, which are implicated in many neurological conditions, are generated during embryogenesis. One of the remaining questions concerns how different dopamine neuron subtypes are specified. A recent paper in Neural Development has revealed features of a spatial and temporal lineage map that, together with other studies, begins to elucidate the developmental origin of distinct neuronal subtypes within the developing midbrain.
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