Review on β-cyclodextrin inclusion complex based chemosensors for heavy metals

Metal ion sensing is the most significant research to overcome the grievous effects caused by metals on the earth’s ecosystem and living organisms. Since β-cd is the widely used host molecule for metal ion sensing, the role of β-cd in the 27 reported chemosensor:β-cyclodextrin systems are analyzed. The main objective of this review is to understand the role of β-cd in metal ions sensing by analyzing the selectivity, sensitivity, and mode of encapsulating the chelating moiety through spectrophotometric, and spectrofluorometric techniques. The matrix, medium, and mechanism reported for the 27 chemosensor:β-cyclodextrin systems are studied and it is observed that the rigid fit offered by the β-cd enhances the metal ion sensing performance of the chemosensors.