Nonbacterial thrombotic endocarditis as the sole manifestation of stage IV gastric cancer: A case report

被引：2

作者：

Shatila W. ^{[1
]}

Rizkallah A. ^{[2
]}

Aldin E.S. ^{[3
]}

Tfayli A. ^{[4
]}

机构：

[1] Department of Internal Medicine, Duke University, 1020 Goldmist Lane, Durham, 27713, NC

[2] Department of Internal Medicine, American University, Beirut Medical Center, PO Box 11-0236, Riad El-Solh, Beirut

[3] Medstar Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, 21239, MD

[4] Division of Hematology/Oncology, American University, Beirut Medical Center, PO Box 11-0236, Riad El-Solh, Beirut

来源：

Journal of Medical Case Reports | / 8卷 / 1期

关键词：

Embolism; Endocarditis; Nonbacterial; Noninfective; Stomach neoplasms; Thrombosis;

D O I：

10.1186/1752-1947-8-267

中图分类号：

学科分类号：

摘要：

Introduction. Nonbacterial thrombotic endocarditis is a very rare complication of malignancy and other hypercoagulable states. It describes the deposition of small sterile smooth or verrucoid vegetations on the valve leaflets, causing a clinical picture similar to that of bacterial endocarditis. The authors reported this case because this is a rare and unusual first manifestation of malignancy generally and of gastric cancer particularly, with only a few reports present in the literature. Case presentation. The authors present a case of a 36-year-old Caucasian male with occult gastric cancer whose first and only manifestation was nonbacterial thrombotic endocarditis causing extensive multi-organ infarctions. Conclusions: An endocarditis not responsive to antibiotics should raise the suspicion of an occult malignancy. Differentiating between an infective endocarditis and a nonbacterial thrombotic endocarditis will cause a radical change in the management which will eventually affect the patient's prognosis. © 2014 Shatila et al.; licensee BioMed Central Ltd.

引用