Stratified Administration of Serotonin 5-HT3 Receptor Antagonists (Setrons) for Chemotherapy-Induced EmesisEconomic Implications

被引：0
作者：
Lisa A. Sanchez
Mark Holdsworth
Sylvia B. Bartel
机构：
[1] PE Applications,Department of Pharmacy Practice
[2] Inc.,Department of Pharmacy
[3] University of New Mexico,undefined
[4] Dana Farber Cancer Institute,undefined
来源：
PharmacoEconomics | 2000年 / 18卷
关键词：
Ondansetron; Metoclopramide; Granisetron; Emetogenic Chemotherapy; Dolasetron;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The serotonin 5-HT3 receptor antagonists or ‘setrons’ have become the standard of care for the prevention of chemotherapy-induced emesis (CIE) and are first-line therapy for acute CIE in healthcare organisations worldwide. However, their superior efficacy versus standard antiemetics comes at a significant cost. Currently, 3 agents are available in the US: ondansetron, granisetron and dolasetron.
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页码：533 / 556
页数：23
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  • [1] Hesketh PJ(1997)Proposal for classifying the acute emetogenicity of cancer chemotherapy J Clin Oncol 15 103-9
  • [2] Kris MG(1988)Controlling emesis in patients receiving cancer chemotherapy Cancer Res 108 89-101
  • [3] Grunberg SM(1990)Ondansetron: a new entity in emesis control DICP Ann Pharmacother 24 51-3
  • [4] Gralla RJ(1991)Therapeutic use as an antiemetic Drugs 41 574-95
  • [5] Kris MG(1993)Ondansetron: an update of its therapeutic use in chemotherapy induced and postoperative nausea and vomiting Drugs 45 931-52
  • [6] Tyson LB(1988)Dose-ranging evaluation of the serotonin antagonist GRC507/75 (GR38032F) when used as an antiemetic in patients receiving anticancer chemotherapy J Clin Oncol 6 659-62
  • [7] Graves T(1989)Dose ranging phase I study of the serotonin antagonist GR38032F for prevention of cisplatin-induced nausea and vomiting J Clin Oncol 7 1137-41
  • [8] Milne RJ(1998)Double-blind, dosefinding study of four intravenous doses of dexamethasone in the prevention of cisplatin-induced acute emesis J ClinOncol 16 2937-42
  • [9] Ondansetron Heel RC.(1997)Comparison of two different doses of ondansetron plus dexamethasone in the prophylaxis of cisplatin-induced emesis Oncology 54 1-6
  • [10] Markham A(1996)PaskaW, Depierre A. Amulticenter, double-blind study comparing placebo, ondansetron and ondansetron plus dexamethasone for the control of cisplatin-induced delayed emesis Ann Oncol 7 945-52
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