Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

被引：0
|
作者：
Kideok Jin
Niranjan B. Pandey
Aleksander S. Popel
机构：
[1] Albany College of Pharmacy and Health Sciences,Department of Pharmaceutical Sciences
[2] Johns Hopkins University School of Medicine,Department of Biomedical Engineering
[3] Johns Hopkins University School of Medicine,Department of Oncology and Sidney Kimmel Comprehensive Cancer Center
来源：
Breast Cancer Research | / 20卷
关键词：
Triple negative breast cancer; Tumor microenvironment; Secretome; Drug repurposing; Maraviroc; Tocilizumab;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Simultaneous glutamine metabolism and PD-L1 inhibition to enhance suppression of triple-negative breast cancer
    Yuxia Tang
    Siqi Wang
    Yang Li
    Chen Yuan
    Jie Zhang
    Ziqing Xu
    Yongzhi Hu
    Haibin Shi
    Shouju Wang
    Journal of Nanobiotechnology, 20
  • [32] Simultaneous glutamine metabolism and PD-L1 inhibition to enhance suppression of triple-negative breast cancer
    Tang, Yuxia
    Wang, Siqi
    Li, Yang
    Yuan, Chen
    Zhang, Jie
    Xu, Ziqing
    Hu, Yongzhi
    Shi, Haibin
    Wang, Shouju
    JOURNAL OF NANOBIOTECHNOLOGY, 2022, 20 (01)
  • [33] The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth
    Qian, Jing
    Ma, Yanxia
    Tahaney, William M.
    Moyer, Cassandra L.
    Lanier, Amanda
    Hill, Jamal
    Coleman, Darian
    Koupaei, Negar
    Hilsenbeck, Susan G.
    Savage, Michelle I.
    Page, Brent D. G.
    Mazumdar, Abhijit
    Brown, Powel H.
    BREAST CANCER RESEARCH, 2024, 26 (01)
  • [34] Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway
    Xie, Qing
    Yang, Zhijie
    Huang, Xuanmei
    Zhang, Zikang
    Li, Jiangbin
    Ju, Jianhua
    Zhang, Hua
    Ma, Junying
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 12 (1)
  • [35] Triple Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1 Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells
    Bajor, Malgorzata
    Graczyk-Jarzynka, Agnieszka
    Marhelava, Katsiaryna
    Kurkowiak, Malgorzata
    Rahman, Arman
    Aura, Claudia
    Russell, Niamh
    Zych, Agata O.
    Firczuk, Malgorzata
    Winiarska, Magdalena
    Gallagher, William M.
    Zagozdzon, Radoslaw
    ANTIOXIDANTS, 2020, 9 (04)
  • [36] Niclosamide sensitizes triple-negative breast cancer cells to ionizing radiation in association with the inhibition of Wnt/β-catenin signaling
    Yin, Lina
    Gao, Yun
    Zhang, Xuxia
    Wang, Jing
    Ding, Defang
    Zhang, Yaping
    Zhang, Junxiang
    Chen, Honghong
    ONCOTARGET, 2016, 7 (27) : 42126 - 42138
  • [37] OSW-1 inhibits tumor growth and metastasis by NFATc2 on triple-negative breast cancer
    Ding, Xiaorong
    Li, Yumei
    Li, Jun
    Yin, Yongmei
    CANCER MEDICINE, 2020, 9 (15): : 5558 - 5569
  • [38] Integrin α9 depletion promotes β-catenin degradation to suppress triple-negative breast cancer tumor growth and metastasis
    Wang, Zhishan
    Li, Yunfei
    Xiao, Yajuan
    Lin, Hsuan-Pei
    Yang, Ping
    Humphries, Brock
    Gao, Tianyan
    Yang, Chengfeng
    INTERNATIONAL JOURNAL OF CANCER, 2019, 145 (10) : 2767 - 2780
  • [39] Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling
    Lee, Eunkyung
    Choi, Ahyoung
    Jun, Yukyung
    Kim, Namhee
    Yook, Jong In
    Kim, Soo Youl
    Lee, Sanghyuk
    Kang, Sang Won
    REDOX BIOLOGY, 2020, 29
  • [40] Sequentially-targeted biomimetic nano drug system for triple-negative breast cancer ablation and lung metastasis inhibition
    Fan, Jialong
    Liu, Bin
    Long, Ying
    Wang, Zhou
    Tong, Chunyi
    Wang, Wei
    You, Peidong
    Liu, Xuanming
    ACTA BIOMATERIALIA, 2020, 113 : 554 - 569
12345