Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

被引:0
|
作者
Kideok Jin
Niranjan B. Pandey
Aleksander S. Popel
机构
[1] Albany College of Pharmacy and Health Sciences,Department of Pharmaceutical Sciences
[2] Johns Hopkins University School of Medicine,Department of Biomedical Engineering
[3] Johns Hopkins University School of Medicine,Department of Oncology and Sidney Kimmel Comprehensive Cancer Center
来源
关键词
Triple negative breast cancer; Tumor microenvironment; Secretome; Drug repurposing; Maraviroc; Tocilizumab;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis
    Jin, Kideok
    Pandey, Niranjan B.
    Popel, Aleksander S.
    BREAST CANCER RESEARCH, 2018, 20
  • [2] CCL5 as a potential immunotherapeutic target in triple-negative breast cancer
    Dandan Lv
    Yan Zhang
    Ha-Jeong Kim
    Lixing Zhang
    Xiaojing Ma
    Cellular & Molecular Immunology, 2013, 10 : 303 - 310
  • [3] CCL5 as a potential immunotherapeutic target in triple-negative breast cancer
    Lv, Dandan
    Zhang, Yan
    Kim, Ha-Jeong
    Zhang, Lixing
    Ma, Xiaojing
    CELLULAR & MOLECULAR IMMUNOLOGY, 2013, 10 (04) : 303 - 310
  • [4] Triple-negative breast cancer displays a unique subset of macrophages dependent on CCL5 signaling
    Rabe, Daniel C.
    Frankenberger, Casey
    Bainer, Russell
    Gilad, Yoav
    Rosner, Marsha Rich
    CANCER RESEARCH, 2014, 74 (19)
  • [5] Endothelial cells promote triple-negative breast cancer cell metastasis via PAI-1 and CCL5 signaling
    Zhang, Wenwen
    Xu, Jing
    Fang, Hehui
    Tang, Lin
    Chen, Weiwei
    Sun, Qian
    Zhang, Qun
    Yang, Fang
    Sun, Zijia
    Cao, Lulu
    Wang, Yucai
    Guan, Xiaoxiang
    FASEB JOURNAL, 2018, 32 (01): : 276 - +
  • [6] PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis
    A Paul
    S Gunewardena
    S R Stecklein
    B Saha
    N Parelkar
    M Danley
    G Rajendran
    P Home
    S Ray
    I Jokar
    G A Vielhauer
    R A Jensen
    O Tawfik
    S Paul
    Cell Death & Differentiation, 2014, 21 : 1469 - 1481
  • [7] PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis
    Paul, A.
    Gunewardena, S.
    Stecklein, S. R.
    Saha, B.
    Parelkar, N.
    Danley, M.
    Rajendran, G.
    Home, P.
    Ray, S.
    Jokar, I.
    Vielhauer, G. A.
    Jensen, R. A.
    Tawfik, O.
    Paul, S.
    CELL DEATH AND DIFFERENTIATION, 2014, 21 (09): : 1469 - 1481
  • [8] Glycolysis inhibition for synergistic phototherapy of triple-negative breast cancer
    Fu, Yuqian
    Bai, Tingjie
    Xue, Panpan
    Chen, Qi
    Deng, Weili
    Yan, Shuangqian
    Zeng, Xuemei
    JOURNAL OF MATERIALS CHEMISTRY B, 2023, 11 (44) : 10717 - 10727
  • [9] A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
    Chen, Ling
    Xu, Guiying
    Song, Xiaoxu
    Zhang, Lianbo
    Chen, Chuyu
    Xiang, Gang
    Wang, Shuxuan
    Zhang, Zijian
    Wu, Fang
    Yang, Xuanming
    Zhang, Lei
    Ma, Xiaojing
    Yu, Jing
    CANCER LETTERS, 2024, 583
  • [10] Molecular mechanism of CD146 nanobody in tumor metastasis inhibition mediating by IL-6/JAK/STAT3 signaling in triple-negative breast cancer
    Huang, Kaiyuan
    Sun, Hexing
    Wu, Chengyu
    Lin, Danping
    Chen, Jinling
    Chen, Yanhan
    Fang, Xinqiang
    Chen, Shuzhao
    Liang, Yuanke
    Lin, Haoyu
    CANCER RESEARCH, 2024, 84 (06)