Monoclonal antibody designed for SARS-nCoV-2 spike protein of receptor binding domain on antigenic targeted epitopes for inhibition to prevent viral entry

被引：0

作者：

Zainularifeen Abduljaleel

Naiyer Shahzad

Syed A. Aziz

Shaheer M. Malik

机构：

[1] Umm Al-Qura University,Science and Technology Unit

[2] Umm Al-Qura University,Department of Medical Genetics, Faculty of Medicine

[3] Ministry of Health (MOH),The Regional Laboratory, Molecular Diagnostics Unit, Department of Molecular Biology

[4] Umm Al-Qura University,Department of Pharmacology and Toxicology, Faculty of Medicine

[5] University of Ottawa,Department of Pathology and Lab Medicine

[6] Umm Al-Qura University,Department of Chemistry, Faculty of Applied Sciences

来源：

Molecular Diversity | 2023年 / 27卷

关键词：

COVID19; Severe acute respiratory syndrome-coronavirus (SARS-CoV-2); Human receptor angiotensin converting enzyme-2 (hACE2); Receptor binding domain (RBD); Monoclonal antibody; Spike (S) protein; Cellular immune responses;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：695 / 708

页数：13

共 50 条

[21] Elucidation of cellular targets and exploitation of the receptor-binding domain of SARS-CoV-2 for vaccine and monoclonal antibody synthesis
Baig, Abdul Mannan
Khaleeq, Areeba
Syeda, Hira
JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (11) : 2792 - 2803
[22] Detection of Binding Sites on SARS-CoV-2 Spike Protein Receptor-Binding Domain by Molecular Dynamics Simulations in Mixed Solvents
Jokinen, Elmeri M.
Gopinath, Krishnasamy
Kurkinen, Sami T.
Pentikainen, Olli T.
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2021, 18 (04) : 1281 - 1289
[23] Refining the N-Termini of the SARS-CoV-2 Spike Protein and Its Discrete Receptor-Binding Domain
D'Ippolito, Robert A.
Drew, Matthew R.
Mehalko, Jennifer
Snead, Kelly
Wall, Vanessa
Putman, Zoe
Esposito, Dominic
DeHart, Caroline J.
JOURNAL OF PROTEOME RESEARCH, 2021, 20 (09) : 4427 - 4434
[24] Global Prevalence of Adaptive and Prolonged Infections' Mutations in the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein
Lennerstrand, Johan
Palanisamy, Navaneethan
VIRUSES-BASEL, 2021, 13 (10):
[25] Display of receptor-binding domain of SARS-CoV-2 Spike protein variants on the Saccharomyces cerevisiae cell surface
Xing, Hongguan
Zhu, Liyan
Wang, Pingping
Zhao, Guoping
Zhou, Zhihua
Yang, Yi
Zou, Hong
Yan, Xing
FRONTIERS IN IMMUNOLOGY, 2022, 13
[26] Role of the GTNGTKR motif in the N-terminal receptor-binding domain of the SARS-CoV-2 spike protein
Behloul, Nouredine
Baha, Sarra
Shi, Ruihua
Meng, Jihong
VIRUS RESEARCH, 2020, 286
[27] Receptor-binding domain of SARS-CoV-2 spike protein efficiently inhibits SARS-CoV-2 infection and attachment to mouse lung
Shin, Hye Jin
Ku, Keun Bon
Kim, Hae Soo
Moon, Hyun Woo
Jeong, Gi Uk
Hwang, Insu
Yoon, Gun Young
Lee, Sunhee
Lee, Sumin
Ahn, Dae-Gyun
Kim, Kyun-Do
Kwon, Young-Chan
Kim, Bum-Tae
Kim, Seong-Jun
Kim, Chonsaeng
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 17 (14): : 3786 - 3794
[28] Plant-Expressed Receptor Binding Domain of the SARS-CoV-2 Spike Protein Elicits Humoral Immunity in Mice
Maharjan, Puna Maya
Cheon, Jinyeong
Jung, Jiyun
Kim, Haerim
Lee, Jaewon
Song, Minjeong
Jeong, Gi Uk
Kwon, Youngchan
Shim, Byoungshik
Choe, Sunghwa
VACCINES, 2021, 9 (09)
[29] Antibody Binding Site Mapping of SARS-CoV Spike Protein Receptor-Binding Domain by a Combination of Yeast Surface Display and Phage Peptide Library Screening
Zhang, Xiaoping
Wang, Jingxue
Wen, Kun
Mou, Zhirong
Zou, Liyun
Che, Xiaoyan
Ni, Bing
Wu, Yuzhang
VIRAL IMMUNOLOGY, 2009, 22 (06) : 407 - 415
[30] Precise location of two novel linear epitopes on the receptor-binding domain surface of MERS-CoV spike protein recognized by two different monoclonal antibodies
Wang, Pan
Ding, Peiyang
Wei, Qiang
Liu, Hongliang
Liu, Yunchao
Li, Qingmei
Xing, Yunrui
Li, Ge
Zhou, Enmin
Zhang, Gaiping
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 195 : 609 - 619

← 1 2 3 4 5 →