Influence of Unilateral Nephrectomy on Aldosterone Reception in the Remaining Kidney in Rats

被引:0
作者
Yu. A. Akimov
N. S. Kositsyn
机构
[1] Russian Academy of Sciences,Institute of Higher Nervous Activity and Neurophysiology
[2] ul. Butlerova 5A,undefined
来源
Biology Bulletin of the Russian Academy of Sciences | 2002年 / 29卷
关键词
Aldosterone; Nuclear Receptor; Mineralocorticoid; Tubule Cell; Unilateral Nephrectomy;
D O I
暂无
中图分类号
学科分类号
摘要
It was shown that the 30th day of compensatory kidney hypertrophy arising as a result of unilateral nephrectomy was accompanied by an increased binding of the mineralocorticoid hormone aldosterone by cytoplasmic receptors of the tubule cells of the remaining kidney. The transfer of aldosterone from cytoplasmic receptors to the nuclear receptors increased in the tubule cells of the hypertrophied kidney. This suggests that at the early stages hypertrophies are expressed as adaptive phenomena and phenomena related to intensified functioning of the organ fulfilling the double load.
引用
收藏
页码:487 / 489
页数:2
相关论文
共 23 条
[1]  
Azhipa Y.(1984)Molecular Mechanisms Underlying the Influence of Neurogenic Dystrophy of Rat Kidneys on Their Sensitivity to Aldosterone Probl. Endokrin. 30 56-undefined
[2]  
Akimov Y.(1991)Plasticity and Function of Brain Corticosteroid Receptors during Aging Acta Endocrin. 125 65-undefined
[3]  
Rodionov A.A.(1978)Memory Facilitating and Antiamnestic Effects of Corticosteroids Pharmacol. Biochem. Behav. 8 81-undefined
[4]  
De Cloet E.R.(1990)Age-Related Changes in Molecular Mechanisms Underlying Hormonal Regulation of Kidney Activity Zh. Evol. Biokh. Fiziol. 26 282-undefined
[5]  
Sutanto W.(1970)Effects of ACTH and Adrenocortical Hormones on the Nervous System Progr. Brain Res. 32 153-undefined
[6]  
Rots N.(1974)Renal Aldosterone Receptors Studies with (3H)Aldosterone and the Antimineralocorticoid ( Proc. Nat. Acad. Sci. (USA) 71 1431-undefined
[7]  
Flood J.F.(1970)H)spirolactone (SC-26304) Progr. Brain Res. 32 250-undefined
[8]  
Vidal D.(1981)Effects of ACTH and Corticosteroids on Animal Behavior J. Steroid Biochem 14 337-undefined
[9]  
Bennett E.(1976)Mineralocorticoid Receptors during Normal Kidney Growth and Compensatory Renal Hypertrophy Byull. Eksp. Biol. Med. 82 1394-undefined
[10]  
Ivanova L.N.(undefined)Comparative Characteristics of Compensatory Hypertrophy of Kidney after Unilateral Nephrectomy in Adult and Senile Rats undefined undefined undefined-undefined