HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm

[1] Andersen MR(2010)Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer Gynecol Oncol 116 378-383

[2] Goff BA(1983)A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer N Engl J Med 309 883-887

[3] Lowe KA(2002)The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms Oncogene 21 2768-2773

[4] Scholler N(1996)Serum tumor marker immunoassays in gynecologic oncology: establishment of reference values Am J Obstet Gynecol 174 107-114

[5] Bergan L(1997)Clinical evaluation of the Byk LIA-mat CA125 II assay: discussion of a reference value Clin Chem 43 491-497

[6] Drescher CW(2006)Proteins with whey-acidic-protein motifs and cancer Lancet Oncol 7 167-174

[7] Paley P(1988)Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach Biometrics 44 837-845

[8] Urban N(2005)Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas Cancer Res 65 2162-2169

[9] Bast RC(2009)Variations in institutional infrastructure, physician specialization and experience, and outcome in ovarian cancer: a systematic review Gynecol Oncol 112 422-436

[10] Klug TL(2006)Comprehensive analysis of HE4 expression in normal and malignant human tissues Mod Pathol 19 847-853

[1] Andersen MR(2010)Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer Gynecol Oncol 116 378-383

[2] Goff BA(1983)A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer N Engl J Med 309 883-887

[3] Lowe KA(2002)The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms Oncogene 21 2768-2773

[4] Scholler N(1996)Serum tumor marker immunoassays in gynecologic oncology: establishment of reference values Am J Obstet Gynecol 174 107-114

[5] Bergan L(1997)Clinical evaluation of the Byk LIA-mat CA125 II assay: discussion of a reference value Clin Chem 43 491-497

[6] Drescher CW(2006)Proteins with whey-acidic-protein motifs and cancer Lancet Oncol 7 167-174

[7] Paley P(1988)Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach Biometrics 44 837-845

[8] Urban N(2005)Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas Cancer Res 65 2162-2169

[9] Bast RC(2009)Variations in institutional infrastructure, physician specialization and experience, and outcome in ovarian cancer: a systematic review Gynecol Oncol 112 422-436

[10] Klug TL(2006)Comprehensive analysis of HE4 expression in normal and malignant human tissues Mod Pathol 19 847-853