Neoadjuvant checkpoint blockade in combination with Chemotherapy in patients with tripe-negative breast cancer: exploratory analysis of real-world, multicenter data

被引:0
作者
Heran Deng
Liying Wang
Na Wang
Kejin Zhang
Yanxia Zhao
Pengfei Qiu
Xiaowei Qi
Danhua Zhang
Fei Xu
Jieqiong Liu
机构
[1] Sun Yat-Sen Memorial Hospital,Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Breast Tumor Center
[2] Sun Yat-Sen University,State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine
[3] Sun Yat-Sen University Cancer Center,undefined
[4] Sun Yat-Sen University,undefined
[5] Xiangya Hospital of Central South University,undefined
[6] Center South University,undefined
[7] Union Hospital Tongji Medical College Huazhong University of Science and Technology,undefined
[8] Huazhong University of Science and Technology,undefined
[9] Shandong Tumor Hospital,undefined
[10] Shandong university,undefined
[11] The Southwest Hospital of AMU,undefined
[12] Army Medical University,undefined
[13] The Second Xiangya Hospital of Central South University,undefined
[14] Center South University,undefined
来源
BMC Cancer | / 23卷
关键词
Tripe-negative breast cancer; Neoadjuvant immunotherapy; Anti-PD-1/L1 antibody; Real-world study;
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[11]  
Mao X(2020)Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women with Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial JAMA Onco. l6 676-821
[12]  
Loi S(2020)Pembrolizumab for Early Triple-Negative Breast Cancer N Engl J Med 382 810-1288
[13]  
Michiels S(2019)A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study Ann Oncol 30 1279-543
[14]  
Adams S(2022)Pathologic complete response (pCR) to neoadjuvant treatment with or without atezolizumab in triple-negative, early high-risk and locally advanced breast cancer: NeoTRIP Michelangelo randomized study Ann Oncol 33 534-1100
[15]  
Loibl S(2020)Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial Lancet 396 1090-520
[16]  
Budczies J(2018)Breast Cancer Immunotherapy: Facts and Hopes Clin Cancer Res 24 511-173
[17]  
Denkert C(2018)Immune-related adverse events for anti-PD-1 and anti-PD-L1 drugs: systematic review and meta-analysis BMJ 360 k793-82
[18]  
Salgado R(2021)The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker Cancer Cell 39 154-2159
[19]  
Chen DS(2020)Effectiveness and Safety of Pyrotinib, and Association of Biomarker With Progression-Free Survival in Patients With HER2-Positive Metastatic Breast Cancer: A Real-World Multicenter Analysis Front Oncol 10 811-581
[20]  
Mellman I(2021)Managing side effects of immune checkpoint inhibitors in breast cancer Crit Rev Oncol Hematol 162 103354-5434