Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial

被引:0
作者
Puja Shankar
Ariel Mueller
Senthil Packiasabapathy
Doris Gasangwa
Melissa Patxot
Brian O’Gara
Shahzad Shaefi
Edward R. Marcantonio
Balachundhar Subramaniam
机构
[1] Beth Israel Deaconess Medical Center,Center for Anesthesia Research Excellence (CARE), Department of Anesthesia, Critical Care and Pain Medicine
[2] Harvard Medical School,Division of General Medicine and Primary Care
[3] Beth Israel Deaconess Medical Center,undefined
[4] Harvard Medical School,undefined
来源
Trials | / 19卷
关键词
Postoperative delirium; Neurocognition; Cardiac surgery; Coronary artery bypass grafting; Montreal Cognitive Assessment; Confusion Assessment Method; Propofol; Acetaminophen; Dexmedetomidine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
[41]   Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial [J].
Kayhan, Gulay Erdogan ;
Sanli, Mukadder ;
Ozgul, Ulku ;
Kirteke, Ramazan ;
Yologlu, Saim .
JOURNAL OF CLINICAL ANESTHESIA, 2018, 50 :5-11
[42]   A randomised controlled trial of dexmedetomidine for delirium in adults undergoing heart valve surgery [J].
Wang, H. -B. ;
Jia, Y. ;
Zhang, C. -B. ;
Zhang, L. ;
Li, Y. -N. ;
Ding, J. ;
Wu, X. ;
Zhang, Z. ;
Wang, J. -H. ;
Wang, Y. ;
Yan, F. -X. ;
Yuan, S. ;
Sessler, D. I. .
ANAESTHESIA, 2023, 78 (05) :571-576
[43]   The Healthy Heart-Mind Trial: Randomized Controlled Trial of Melatonin for Prevention of Delirium [J].
Ford, Andrew H. ;
Flicker, Leon ;
Kelly, Rachael ;
Patel, Hema ;
Passage, Jurgen ;
Wibrow, Bradley ;
Anstey, Matthew ;
Edwards, Mark ;
Almeida, Osvaldo P. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2020, 68 (01) :112-119
[44]   Postoperative infusion of dexmedetomidine via intravenous patient-controlled analgesia for prevention of postoperative delirium in elderly patients undergoing surgery [J].
Xie, Kangjie ;
Chen, Jinyan ;
Tian, Lili ;
Gu, Fulei ;
Pan, Yafei ;
Huang, Zhangxiang ;
Fang, Jun ;
Yu, Weifeng ;
Zhou, Huidan .
AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2023, 35 (10) :2137-2144
[45]   Postoperative infusion of dexmedetomidine via intravenous patient-controlled analgesia for prevention of postoperative delirium in elderly patients undergoing surgery [J].
Kangjie Xie ;
Jinyan Chen ;
Lili Tian ;
Fulei Gu ;
Yafei Pan ;
Zhangxiang Huang ;
Jun Fang ;
Weifeng Yu ;
Huidan Zhou .
Aging Clinical and Experimental Research, 2023, 35 :2137-2144
[46]   Effect of Intraoperative Dexmedetomidine Use on Postoperative Delirium in the Elderly After Laryngectomy: A Randomized Controlled Clinical Trial [J].
Liu, Weiwei ;
Wang, Yiru ;
Chen, Kaizheng ;
Ye, Min ;
Lu, Weisha ;
Chen, Keyu ;
Shen, Xia .
DRUG DESIGN DEVELOPMENT AND THERAPY, 2023, 17 :2933-2941
[47]   Intravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial [J].
Zeilmaker-Roest, Gerdien A. ;
van Rosmalen, Joost ;
van Dijk, Monique ;
Koomen, Erik ;
Jansen, Nicolaas J. G. ;
Kneyber, Martin C. J. ;
Maebe, Sofie ;
van den Berghe, Greet ;
Vlasselaers, Dirk ;
Bogers, Ad J. J. C. ;
Tibboel, Dick ;
Wildschut, Enno D. .
TRIALS, 2018, 19
[48]   Effect of remimazolam versus propofol anesthesia on postoperative delirium in neurovascular surgery: study protocol for a randomized controlled, non-inferiority trial [J].
Kim, Jeayoun ;
Lee, Seungwon ;
Park, Boram ;
Sim, Woo Seog ;
Ahn, Hyun Joo ;
Park, Mi-Hye ;
Jeong, Ji Seon .
PERIOPERATIVE MEDICINE, 2024, 13 (01)
[49]   Feasibility of low-dose dexmedetomidine for prevention of postoperative delirium after intracranial operations: a pilot randomized controlled trial [J].
Xuan He ;
Kun-Ming Cheng ;
Yu-Qing Duan ;
Shan-Shan Xu ;
Hao-Ran Gao ;
Ming-Yue Miao ;
Hong-Liang Li ;
Kai Chen ;
Yan-Lin Yang ;
Linlin Zhang ;
Hong-Qiu Gu ;
Jian-Xin Zhou .
BMC Neurology, 21
[50]   Intravenous acetaminophen for postoperative delirium in older patients recovering from major non-cardiac surgery: a randomised-controlled study protocol [J].
Zheng, Miao ;
Wang, Baoshan ;
Mao, Menghan ;
Wu, Yuling ;
Wang, Zhenhong ;
Yang, Liqun .
BMJ OPEN, 2025, 15 (05)