Establishment of platform for screening insulin-like growth factor-1 receptor inhibitors and evaluation of novel inhibitors

被引:0
作者
Lin-jiang Tong
Hua Xie
Ting Peng
Xiao-feng Liu
Xian-liang Xin
Xun Huang
Si-meng Chen
Hong-yan Liu
Hong-lin Li
Mei-yu Geng
Ming Yin
Jian Ding
机构
[1] School of Pharmacy,Division of Antitumor Pharmacology
[2] Shanghai Jiao Tong University,undefined
[3] State Key Laboratory of Drug Research,undefined
[4] Shanghai Institute of Materia Medica,undefined
[5] Chinese Academy of Sciences,undefined
[6] Shanghai Key Laboratory of Chemical Biology,undefined
[7] School of Pharmacy,undefined
[8] East China University,undefined
来源
Acta Pharmacologica Sinica | 2011年 / 32卷
关键词
insulin like growth factor 1 receptor (IGF1R); anticancer drug; enzyme-linked immunosorbent assay (ELISA); hematoxylin; cell; proliferation; apoptosis; HL-60 cell line;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:930 / 938
页数:8
相关论文
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[1]  
Laviola L(2007)The IGF-I signaling pathway Curr Pharm Des 13 663-9
[2]  
Natalicchio A(2000)Structure and function of the type 1 insulin-like growth factor receptor Cell Mol Life Sci 57 1050-93
[3]  
Giorgino F(2004)Insulin-like growth factors and neoplasia Nat Rev Cancer 4 505-18
[4]  
Adams TE(2007)The role of the IGF system in cancer growth and metastasis: overview and recent insights Endocr Rev 28 20-47
[5]  
Epa VC(2007)Disrupting insulin-like growth factor signaling as a potential cancer therapy Mol Cancer Ther 6 1-12
[6]  
Garrett TP(2010)A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines Mol Cancer Ther 9 1809-19
[7]  
Ward CW(2009) and Clin Cancer Res 15 5117-25
[8]  
Pollak MN(2007)Inhibition of insulin-like growth factor 1 receptor by CP-751871 radiosensitizes non-small cell lung cancer cells Bioorg Med Chem Lett 17 4026-9
[9]  
Schernhammer ES(2010)Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs Biochem Biophys Res Commun 399 727-32
[10]  
Hankinson SE(2010)IGF-1 receptor inhibition by picropodophyllin in medulloblastoma Biochem Pharmacol 80 455-62