Rapid Determination of Some Cephalosporins Using Immobilized para-Dimethylaminobenzaldehyde

被引：0

作者：

Tumskaya, A. V. ^{[1
]}

Kosyreva, I. V. ^{[1
]}

机构：

[1] Chernyshevsky Saratov Natl Res State Univ, Saratov 410012, Russia

来源：

JOURNAL OF ANALYTICAL CHEMISTRY | 2024年 / 79卷 / 02期

基金：

俄罗斯科学基金会;

关键词：

rapid determination; indicator papers; colorimetry; para-dimethylaminobenzaldehyde; cephalosporins; CEPHALEXIN;

D O I：

10.1134/S1061934824020138

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Indicator papers with immobilized para-dimethylaminobenzaldehyde are proposed for the visual-colorimetric and colorimetric determination of antibacterial compounds of the cephalosporin group (cephalexin, cefuroxime, cefotaxime, ceftriaxone, cefazolin) using a smartphone camera. The effect of conditions and the type of the photorecording device is assessed. The accuracy of the developed rapid procedures is estimated using the added-found method; the procedures are characterized by the satisfactory reproducibility of results (RSD does not exceed 19%). An analysis of drugs-"Aksosef" tablets and "Cephalexin" capsules-is carried out; the found contents of cephalosporins are consistent with the declared ranges of their contents in the drugs.

引用

页码：141 / 147

页数：7

共 17 条

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