Rapid Determination of Some Cephalosporins Using Immobilized para-Dimethylaminobenzaldehyde

被引：1

作者：

Tumskaya, A. V. ^{[1
]}

Kosyreva, I. V. ^{[1
]}

机构：

[1] Chernyshevsky Saratov Natl Res State Univ, Saratov 410012, Russia

来源：

JOURNAL OF ANALYTICAL CHEMISTRY | 2024年 / 79卷 / 02期

基金：

俄罗斯科学基金会;

关键词：

rapid determination; indicator papers; colorimetry; para-dimethylaminobenzaldehyde; cephalosporins; CEPHALEXIN;

D O I：

10.1134/S1061934824020138

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Indicator papers with immobilized para-dimethylaminobenzaldehyde are proposed for the visual-colorimetric and colorimetric determination of antibacterial compounds of the cephalosporin group (cephalexin, cefuroxime, cefotaxime, ceftriaxone, cefazolin) using a smartphone camera. The effect of conditions and the type of the photorecording device is assessed. The accuracy of the developed rapid procedures is estimated using the added-found method; the procedures are characterized by the satisfactory reproducibility of results (RSD does not exceed 19%). An analysis of drugs-"Aksosef" tablets and "Cephalexin" capsules-is carried out; the found contents of cephalosporins are consistent with the declared ranges of their contents in the drugs.

引用

页码：141 / 147

页数：7

共 18 条

[1] Novel spectrophotometric determinations of some cephalosporins following azo dye formation with p-dimethylaminobenzaldehyde [J].

Adegoke, Olajire A. ;

Quadri, Monsurat O. .

ARABIAN JOURNAL OF CHEMISTRY, 2016, 9 :S1272-S1282

[2] DIGITAL COLORIMETRY OF INDICATOR TEST SYSTEMS USING SMARTPHONE AND CHEMOMETRIC ANALYSIS IN DETERMINING TETRACYCLINES IN MEDICINAL PREPARATIONS [J].

Amelin, V. G. ;

Shogah, Z. A. C. ;

Bolshakov, D. S. ;

Tretyakov, A., V .

IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA I KHIMICHESKAYA TEKHNOLOGIYA, 2022, 65 (07) :17-27

[3]

[Anonymous], 2019, Order of the Government of the Russian Federation

[4]

[Anonymous], 2018, General pharmacopoeial monograph GPM.1.1.0012.15: Validation of analytical methods, State Pharmacopoeia of the Russian Federation XIV, V1

[5] Use of household color-recording devices in quantitative chemical analysis [J].

Apyari, V. V. ;

Gorbunova, M. V. ;

Isachenko, A. I. ;

Dmitrienko, S. G. ;

Zolotov, Yu. A. .

JOURNAL OF ANALYTICAL CHEMISTRY, 2017, 72 (11) :1127-1137

[6] Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity [J].

Bozic, Bojana ;

Korac, Jelena ;

Stankovic, Dalibor M. ;

Stanic, Marina ;

Romanovic, Mima ;

Pristov, Jelena Bogdanovic ;

Spasic, Snezana ;

Popovic-Bijelic, Ana ;

Spasojevic, Ivan ;

Bajcetic, Milica .

FREE RADICAL BIOLOGY AND MEDICINE, 2018, 129 :279-285

[7] New valid spectrofluorimetric method for determination of selected cephalosporins in different pharmaceutical formulations using safranin as fluorophore [J].

Derayea, Sayed M. ;

Ahmed, Hytham M. ;

Abdelmageed, Osama H. ;

Haredy, Ahmed M. .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2016, 153 :655-660

[8] Optimization and validation of spectrofluorimetric method for determination of cefadroxile and cefuroxime sodium in pharmaceutical formulations [J].

Elbashir, Abdalla A. ;

Ahmed, Shazalia M. A. ;

Aboul-Enein, Hassan Y. .

LUMINESCENCE, 2013, 28 (04) :490-495

[9]

FAIGL F, 1962, KAPELNYI ANALIZ ORGA

[10]

Gabidulina M.K., 2018, MAT INT SCI C COMPUT, P93

← 1 2 →