Dietary Grape Seed Proanthocyanidins Inhibit UVB-Induced Cyclooxygenase-2 Expression and Other Inflammatory Mediators in UVB-Exposed Skin and Skin Tumors of SKH-1 Hairless Mice

被引:0
作者
Som D. Sharma
Santosh K. Katiyar
机构
[1] Birmingham Veteran Affairs Medical Center,Department of Dermatology
[2] University of Alabama,undefined
来源
Pharmaceutical Research | 2010年 / 27卷
关键词
chemoprevention; COX-2; grape seed proanthocyanidins; skin cancer; ultraviolet radiation;
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学科分类号
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页码:1092 / 1102
页数:10
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[1]  
Housman TS(2003)Skin cancer is among the most costly of all cancers to treat for the Medicare population J Am Acad Dermatol. 48 425-9
[2]  
Feldman SR(2000)Kinetics of UV light-induced cyclobutane pyrimidine dimers in human skin Photochem Photobiol. 72 788-93
[3]  
Williford PM(2007) An immunohistochemical analysis of both epidermis and dermis Toxicol Appl Pharmacol. 224 220-7
[4]  
Fleischer AB(1978)Interleukin-12 and photocarcinogenesis Br J Clin Pharmacol. 5 431-6
[5]  
Goldman ND(1994)Increased prostaglandins E2 and F2alpha in human skin at 6 and 24 h after ultraviolet B irradiation (290–320 nm) J Leukoc Biol. 56 769-75
[6]  
Acostamadiedo JM(1996)The role of IL-4, IL-10, and TNF-alpha in the immune suppression induced by ultraviolet radiation Photochem Photobiol. 63 355-447
[7]  
Katiyar SK(2009)Photocarcinogenesis: mechanisms, models and human health implications J Invest Dermatol. 129 1258-70
[8]  
Matsui MS(2002)Inhibition of UVB-induced skin tumor development by drinking green tea polyphenols is mediated through DNA repair and subsequent inhibition of inflammation Food Chemical Toxicol. 40 599-607
[9]  
Mukhtar H(2003)Safety evaluation of proanthocyanidins-rich extract from grape seeds J Med Food. 6 291-9
[10]  
Katiyar SK(1994)Polyphenolics in grape seeds-biochemistry and functionality Phytochemistry 36 781-9