Carnitine and AcylcarnitinesPharmacokinetic, Pharmacological and Clinical Aspects

被引：0
作者：
Stephanie E. Reuter
Allan M. Evans
机构：
[1] University of South Australia,School of Pharmacy & Medical Sciences
[2] University of South Australia,Sansom Institute for Health Research
来源：
Clinical Pharmacokinetics | 2012年 / 51卷 / 9期
关键词：
Carnitine; Chronic Fatigue Syndrome; Carnitine Concentration; Primary Carnitine Deficiency; Acylcarnitine Concentration;
D O I：
10.1007/BF03261931
中图分类号：
学科分类号：
摘要：
L-Carnitine (levocarnitine) is a naturally occurring compound found in all mammalian species. The most important biological function of L-carnitine is in the transport of fatty acids into the mitochondria for subsequent β-oxidation, a process which results in the esterification of L-carnitine to form acylcarnitine derivatives. As such, the endogenous carnitine pool is comprised of L-carnitine and various short-, medium-and long-chain acylcarnitines.
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页码：553 / 572
页数：19
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