Runx3 specifies lineage commitment of innate lymphoid cells

被引:0
作者
Takashi Ebihara
Christina Song
Stacy H Ryu
Beatrice Plougastel-Douglas
Liping Yang
Ditsa Levanon
Yoram Groner
Michael D Bern
Thaddeus S Stappenbeck
Marco Colonna
Takeshi Egawa
Wayne M Yokoyama
机构
[1] Howard Hughes Medical Institute,Department of Pathology and Immunology
[2] Washington University School of Medicine,Division of Rheumatology, Department of Medicine
[3] Washington University School of Medicine,Department of Molecular Genetics
[4] Washington University School of Medicine,undefined
[5] The Weizmann Institute of Science,undefined
[6] Medical Scientist Training Program,undefined
[7] Washington University School of Medicine,undefined
来源
Nature Immunology | 2015年 / 16卷
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摘要
The transcriptional control of lineage commitment to various ILC subsets is incompletely understood. Yokoyama and colleagues show that Runx3 is essential for the normal development of ILC1 and ILC3 cells but not ILC2 cells.
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页码:1124 / 1133
页数:9
相关论文
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