Drug-induced pneumonitis detected earlier by 18F-FDG-PET than by high-resolution CT: a case report with non-Hodgkin’s lymphoma

被引：0
作者：
Tomohiko Yamane
Osami Daimaru
Satoshi Ito
Takeshi Nagata
Kazuhiko Yoshiya
Nobuyuki Fukaya
Shinichi Ito
Teruhiko Imai
Hideo Uchida
机构：
[1] Daiyukai General Hospital,Department of Radiology
[2] Daiyukai General Hospital,Department of Hematology
[3] Saiseikai Nara Hospital,Department of Internal Medicine
来源：
Annals of Nuclear Medicine | 2008年 / 22卷
关键词：
F-FDG-PET; High-resolution CT; Drug-induced pneumonitis; Chemotherapy; Malignant lymphoma;
D O I：
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中图分类号：
学科分类号：
摘要：
Drug-induced pneumonitis is a serious and an unpredictable side effect of chemotherapy in patients with malignant lymphoma. We present the case of a 51-year-old man who developed drug-induced pneumonitis during chemotherapy for non-Hodgkin’s lymphoma in which pneumonitis was detected earlier by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) than by high-resolution computed tomography (HRCT). After five courses of chemotherapy, 18F-FDG-PET was performed for assessing residual lesions, and diffuse lung uptake was incidentally observed. No symptoms were present, and HRCT performed immediately following PET revealed no abnormalities. Mild dyspnea appeared 3 days after PET, and additional HRCT revealed patchy ground-glass opacities disseminated with the appearance of interlobular septum thickening. Drug-induced pneumonitis was finally diagnosed, and treatment was initiated. 18F-FDG-PET can be an imaging modality for detecting drug-induced pneumonitis at an extremely early stage in which HRCT is incapable of revealing any abnormal changes.
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页码：719 / 722
页数：3
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