Pharmacological Activity of 4,5-Dihydropyrazole Derivatives (Review)

被引：0
|
作者：
D. D. Korablina
N. I. Vorozhtsov
L. A. Sviridova
E. I. Kalenikova
O. S. Medvedev
机构：
[1] Moscow State University,
来源：
Pharmaceutical Chemistry Journal | 2016年 / 50卷
关键词：
dihydropyrazole; pyrazoline; anti-inflammatory activity; antitumor activity; antimicrobial activity; pharmacological activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The various types of pharmacological activity of 4,5-dihydropyrazole derivatives are reviewed. Attention is focused on the influence of various substituents in the dihydropyrazole core on the pharmacological effects of these compounds.
引用
收藏
页码：281 / 295
页数：14
相关论文
共 50 条
  • [11] Molecular dynamics simulation study on the inhibitory mechanism of RIPK1 by 4,5-dihydropyrazole derivatives
    Zhang, Yurou
    Wang, Song
    Ren, Aimin
    Guan, Shanshan
    Jingwen, E.
    Luo, Zhijian
    Yang, Zhijie
    Zhang, Xinyue
    Du, Juan
    Zhang, Hao
    MOLECULAR PHYSICS, 2023, 121 (03)
  • [12] Synthesis of 4-methylcoumarin derivatives containing 4,5-dihydropyrazole moiety to scavenge radicals and to protect DNA
    Xiao, Chuan
    Luo, Xu-Yang
    Li, De-Jun
    Lu, Hang
    Liu, Zai-Qun
    Song, Zhi-Guang
    Jin, Ying-Hua
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 53 : 159 - 167
  • [13] Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents
    Liu, Xin-Hua
    Ruan, Ban-Feng
    Liu, Jing-Xin
    Song, Bao-An
    Jing, Ling-Hong
    Li, Jun
    Yang, Yang
    Zhu, Hai-Liang
    Qi, Xing-Bao
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (10) : 2916 - 2920
  • [14] Microwave-assisted reaction of 2′-hydroxychalcones with hydrazides to synthesize flavanone hydrazone and 4,5-dihydropyrazole derivatives
    Nie, Aihua
    Huang, Ziwei
    JOURNAL OF COMBINATORIAL CHEMISTRY, 2006, 8 (05): : 655 - 658
  • [15] Iodine mediated a simple strategy for the synthesis of β,γ-unsaturated-α-ketoesters and its application for the synthesis of 4,5-dihydropyrazole derivatives
    Anil Pommidi
    Asha Begum Shaik
    Anindita Chatterjee
    Vijaya Laxmi Somarapu
    Journal of the Iranian Chemical Society, 2020, 17 : 1545 - 1553
  • [16] Iodine mediated a simple strategy for the synthesis of β,γ-unsaturated-α-ketoesters and its application for the synthesis of 4,5-dihydropyrazole derivatives
    Pommidi, Anil
    Shaik, Asha Begum
    Chatterjee, Anindita
    Somarapu, Vijaya Laxmi
    JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2020, 17 (07) : 1545 - 1553
  • [17] Synthesis and molecular docking study of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential antitumor agents
    Liu, Xin-Hua
    Liu, Hui-Feng
    Chen, Jin
    Yang, Yang
    Song, Bao-An
    Bai, Lin-Shan
    Liu, Jing-Xin
    Zhu, Hai-Liang
    Qi, Xing-Bao
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (19) : 5705 - 5708
  • [18] Design and synthesis of novel 5-phenyl-N-piperidine ethanone containing 4,5-dihydropyrazole derivatives as potential antitumor agents
    Liu, Xin-Hua
    Li, Jun
    Shi, Jing Bo
    Song, Bao-An
    Qi, Xing-Bao
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 51 : 294 - 299
  • [19] Experimental and computational studies on propanone derivatives of quinoxalin-6-yl-4,5-dihydropyrazole as inhibitors of mild steel corrosion in hydrochloric acid
    Olasunkanmi, Lukman O.
    Ebenso, Eno E.
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2020, 561 (561) : 104 - 116
  • [20] Synthesis and Characterization of 1,4-Diaryl-3-ethoxycarbonyl-5-(2-phenyl-1,2,3-triazoloylcarbonyl)-4,5-dihydropyrazole Derivatives
    Wu, Xiaolong
    Ye, Jiawei
    Yang, Debao
    Liu, Fangming
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2010, 30 (10) : 1502 - 1507
12345