Effect of ketamine combined with magnesium sulfate in neuropathic pain patients (KETAPAIN): study protocol for a randomized controlled trial

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作者
Noémie Delage
Véronique Morel
Pascale Picard
Fabienne Marcaillou
Bruno Pereira
Gisèle Pickering
机构
[1] CHU de Clermont-Ferrand,Centre d’Evaluation et de Traitement de la Douleur
[2] CHU Clermont-Ferrand,Centre de Pharmacologie Clinique, Bâtiment 3C, CIC Inserm 1405
[3] BP 69,Inserm, U1107 Neuro
[4] CHU de Clermont-Ferrand,Dol, Pharmacologie Fondamentale et Clinique de la Douleur, Laboratoire de Pharmacologie, Faculté de Médecine
[5] Délégation Recherche Clinique & Innovation - Villa annexe IFSI,undefined
[6] Université Clermont Auvergne,undefined
来源
Trials | / 18卷
关键词
Ketamine; Neuropathic pain; Magnesium sulfate; -methyl-; -aspartate receptor; Placebo;
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[1]  
Finnerup NB(2016)Neuropathic pain: an updated grading system for research and clinical practice Pain. 157 1599-606
[2]  
Haroutounian S(2010)NMDA receptor antagonists for the treatment of neuropathic pain Pain Med. 11 1726-42
[3]  
Kamerman P(2006)The antiallodynic effect of NMDA antagonists in neuropathic pain outlasts the duration of the in vivo NMDA antagonism Neuropharmacology. 51 12-7
[4]  
Baron R(2000)Targeting the J Pain Symptom Manage 20 358-73
[5]  
Bennett DL(1993)-methyl- Brain Res. 605 164-8
[6]  
Bouhassira D(2001)-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions Eur J Pharmacol. 429 71-8
[7]  
Cruccu G(1996)Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviours in a rat model of peripheral mononeuropathy Brain Res. 715 51-62
[8]  
Freeman R(2001)NMDA receptors as targets for drug action in neuropathic pain Pain. 91 101-9
[9]  
Hansson P(2011)Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy Anesthesiology. 115 165-74
[10]  
Nurmikko T(2008)Comparison of the effects of MK801, ketamine and memantine on responses of spinal dorsal horn neurons in a rat model of mononeuropathy Pharmacol Biochem Behav. 90 676-85