Features of the tautomerism of some α-substituted pyridines

被引：0
|
作者：
Kereselidze J.A. [1 ]
Zarkua T.Sh. [1 ]
机构：
[1] I. Dzhavakhishvili State University
来源：
Chemistry of Heterocyclic Compounds | 2000年 / 36卷 / 10期
关键词：
2-amino-; and; 2-methylpyridine; Keto-enol and amino-imino tautomerism; Pyrid-2-one; Quantum-chemical calculations; Tautomeric equilibrium constants;
D O I：
10.1023/A:1002860430962
中图分类号：
学科分类号：
摘要：
The AM1 quantum-chemical semi-empirical method was used to calculate the values of the enthalpy of activation (ΔΔH£), the heats of reaction (ΔΔH), and the tautomeric equilibrium constants (KT) for several α-substituted pyridines. It was found that the keto-enol tautomeric conversion in α-pyridone occurs more readily than the amino-imino conversion in 2-aminopyridine but in 2-methylpyridine the tautomeric equilibrium does not exist at all.
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页码：1161 / 1163
页数：2
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