Activation-free one-pot alkynylation–cyclization synthesis of 2-substituted 4-azaindoles and indoles

被引：0
作者：
Timo Lessing
Thomas J. J. Müller
机构：
[1] Heinrich-Heine-Universität Düsseldorf,Institut für Organische Chemie und Makromolekulare Chemie, Lehrstuhl für Organische Chemie
来源：
Chemistry of Heterocyclic Compounds | 2018年 / 54卷
关键词：
4-azaindoles; heterocycles; indoles; alkynylation; cyclization; one-pot reaction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
2-Substituted 4-azaindoles and indoles are rapidly and efficiently prepared in an activation-free Pd-catalyzed alkynylation–cyclization sequence starting from 3-amino-2-bromopyridine or o-bromoaniline and terminal alkynes in a one-pot fashion.
引用
收藏
页码：334 / 338
页数：4
相关论文
共 151 条
[1]  
Netz N(2015)undefined Mar. Drugs 13 4814-undefined
[2]  
Opatz T(2003)undefined Curr. Med. Chem. 10 1113-undefined
[3]  
Aygun A(2005)undefined Life Sci. 78 442-undefined
[4]  
Pindur U(2005)undefined J. Org. Chem. 70 5528-undefined
[5]  
Gul W(2013)undefined RSC Adv. 3 945-undefined
[6]  
Hamann MT(2004)undefined Photochem. Photobiol. 79 211-undefined
[7]  
Schmidt AM(2008)undefined Adv. Synth. Catal. 350 2153-undefined
[8]  
Eilbracht P(2006)undefined Chem. Rev. 106 2875-undefined
[9]  
Johansson H(2005)undefined Chem. Rev. 105 2873-undefined
[10]  
Bøgeløv Jørgensen T(2004)undefined Chem. Rev. 104 2285-undefined
12345678910