Vessel maneuvers: Zinc fingers promote angiogenesis

被引：0

作者：

Renata Pasqualini

Carlos F. Barbas

Wadih Arap

机构：

[1] M.D. Anderson Cancer Center,

[2] The University of Texas,undefined

[3] The Scripps Research Institute,undefined

来源：

Nature Medicine | 2002年 / 8卷

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D O I：

暂无

中图分类号：

学科分类号：

摘要：

Zinc-finger transcription factors can be engineered to target specific genes. Now this approach is applied successfully to a clinically relevant setting in mice—promotion of angiogenesis. (pages 1427–1432)

引用

页码：1353 / 1354

页数：1

共 12 条

[1]

Rebar EJ(2002)Induction of angiogenesis in a mouse model using engineered transcription factors Nature Med. 8 1427-1432

[2]

Beerli RR(2002)Engineering polydactyl zinc-finger transcription factors Nature Biotechnol. 20 135-141

[3]

Barbas CF(2001)Design and selection of novel Cys2His2 zinc finger proteins Annu. Rev. Biochem. 70 313-340

[4]

Pabo CO(2001)A versatile framework for the design of ligand-dependent, transgene-specific transcription factors Mol. Ther. 3 262-273

[5]

Peisach E(2002)Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors Proc. Natl. Acad. Sci. 99 13296-13301

[6]

Grant RA(2000)Angiopoietin-1 protects the adult vasculature against plasma leakage Nature Med. 6 460-463

[7]

Xu L(2000)Positive and negative regulation of endogenous genes by designed transcription factors Proc. Natl. Acad. Sci. USA 97 1495-1500

[8]

Guan X(undefined)undefined undefined undefined undefined-undefined

[9]

Thurston G(undefined)undefined undefined undefined undefined-undefined

[10]

Beerli RR(undefined)undefined undefined undefined undefined-undefined

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