Glucose rapidly decreases plasma membrane GLUT4 content in rat skeletal muscle

被引：0

作者：

André Marette

Dimitrios Dimitrakoudis

Qing Shi

Carol D. Rodgers

Amira Klip

Mladen Vranic

机构：

[1] Laval University Hospital Research Centre (CHUL),Department of Physiology and Lipid Research Unit

[2] University of Toronto,Department of Physiology, Faculty of Medicine

[3] University of Toronto,Department of Medicine, Faculty of Medicine

[4] The Hospital for Sick Children,Department of Programme in Cell Biology

来源：

Endocrine | 1999年 / 10卷

关键词：

Glucose transporter; GLUT1; phlorizin; glycemia; streptozotocin;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We have previously demonstrated that chronic hyperglycemia per se decreases GLUT4 glucose transporter expression and plasma membrane content in mildly streptozotocin- (STZ) diabetic rats (Biochem. J. 284, 341–348, 1992). In the present study, we investigated the effect of an acute rise in glycemia on muscle GLUT4 and GLUT1 protein contents in the plasma membrane, in the absence of insulin elevation. Four experimental groups of rats were analyzed in the postabsorptive state:Control rats.Hyperglycemic STZ-diabetic rats with moderately reduced fasting insulin levels.STZ-diabetic rats made normoglycemic with phlorizin treatment.Phlorizin-treated (normoglycemic) STZ-diabetic rats infused with glucose for 40 min.

引用

页码：13 / 18

页数：5

共 50 条

[31] Dipeptidyl peptidase IV inhibition upregulates GLUT4 translocation and expression in heart and skeletal muscle of spontaneously hypertensive rats
Giannocco, Gisele
Oliveira, Kelen C.
Crajoinas, Renato O.
Venturini, Gabriela
Salles, Thiago A.
Fonseca-Alaniz, Miriam H.
Maciel, Rui M. B.
Girardi, Adriana C. C.
EUROPEAN JOURNAL OF PHARMACOLOGY, 2013, 698 (1-3) : 74 - 86
[32] Dexamethasone stimulates the expression of GLUT1 and GLUT4 proteins via different signalling pathways in L6 skeletal muscle cells
Ewart, HS
Somwar, R
Klip, A
FEBS LETTERS, 1998, 421 (02): : 120 - 124
[33] Expression of the glucose transporters GLUT1, GLUT3, GLUT4 and GLUT12 in human cancer cells
Carly Barron
Evangelia Tsiani
Theodoros Tsakiridis
BMC Proceedings, 6 (Suppl 3)
[34] EXPRESSION AND CELLULAR-LOCALIZATION OF GLUCOSE TRANSPORTERS (GLUT1, GLUT3, GLUT4) DURING DIFFERENTIATION OF MYOGENIC CELLS ISOLATED FROM RAT FETUSES
GUILLETDENIAU, I
LETURQUE, A
GIRARD, J
JOURNAL OF CELL SCIENCE, 1994, 107 : 487 - 496
[35] Changes in photoperiod alter Glut4 expression in skeletal muscle of C57BL/6J mice
Tashiro, Ayako
Shibata, Satomi
Takai, Yusuke
Uchiwa, Tatsuhiro
Furuse, Mitsuhiro
Yasuo, Shinobu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 485 (01) : 82 - 88
[36] Insulin-responsive glucose transporters - GLUT8 and GLUT4 are expressed in the developing mammalian brain
Sankar, R
Thamotharan, S
Shin, D
Moley, KH
Devaskar, SU
MOLECULAR BRAIN RESEARCH, 2002, 107 (02): : 157 - 165
[37] Low-Dose Acrolein, an Endogenous and Exogenous Toxic Molecule, Inhibits Glucose Transport via an Inhibition of Akt-Regulated GLUT4 Signaling in Skeletal Muscle Cells
Wang, Ching-Chia
Chen, Huang-Jen
Chan, Ding-Cheng
Chiu, Chen-Yuan
Liu, Shing-Hwa
Lan, Kuo-Cheng
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (13)
[38] Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle - Implications for glucose toxicity
Baron, AD
Zhu, JS
Weldon, H
Maianu, L
Garvey, WT
JOURNAL OF CLINICAL INVESTIGATION, 1995, 96 (06) : 2792 - 2801
[39] Decreased diabetes-induced glycemic impairment in WKY and SHR involves enhanced skeletal muscle Slc2a4/GLUT4 expression
Alves-Wagner, Ana Barbara
Sabino-Silva, Robinson
Campello, Raquel S.
Mori, Rosana C.
Machado, Ubiratan F.
DIABETOLOGY & METABOLIC SYNDROME, 2014, 6
[40] A novel quantitative assay for analysis of GLUT4 translocation using high content screening
Komakula, SaiSantosh Babu
Tiwari, Ashok Kumar
Singh, Shashi
BIOMEDICINE & PHARMACOTHERAPY, 2021, 133

← 1 2 3 4 5 →