IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling

[1] Soengas MS(2003)Apoptosis and melanoma chemoresistance Oncogene 22 3138-3151

[2] Lowe SW(2006)Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model Int Rev Cytol 251 131-158

[3] Hersey P(2016)Melanoma and the unfolded protein response Cancers 8 30-497

[4] Zhuang L(2014)Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress J Invest Dermatol 134 488-958

[5] Zhang XD(2015)Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma Cell Death Differ 22 946-1417

[6] Sykes EK(2014)Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma J Clin Invest 124 1406-529

[7] Mactier S(2007)Signal integration in the endoplasmic reticulum unfolded protein response Nat Rev Mol Cell Biol 8 519-789

[8] Christopherson RI(2005)The mammalian unfolded protein response Annu Rev Biochem 74 739-1086

[9] Croft A(2011)The unfolded protein response: from stress pathway to homeostatic regulation Science 334 1081-891

[10] Tay KH(2001)XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor Cell 107 881-367

[1] Soengas MS(2003)Apoptosis and melanoma chemoresistance Oncogene 22 3138-3151

[2] Lowe SW(2006)Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model Int Rev Cytol 251 131-158

[3] Hersey P(2016)Melanoma and the unfolded protein response Cancers 8 30-497

[4] Zhuang L(2014)Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress J Invest Dermatol 134 488-958

[5] Zhang XD(2015)Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma Cell Death Differ 22 946-1417

[6] Sykes EK(2014)Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma J Clin Invest 124 1406-529

[7] Mactier S(2007)Signal integration in the endoplasmic reticulum unfolded protein response Nat Rev Mol Cell Biol 8 519-789

[8] Christopherson RI(2005)The mammalian unfolded protein response Annu Rev Biochem 74 739-1086

[9] Croft A(2011)The unfolded protein response: from stress pathway to homeostatic regulation Science 334 1081-891

[10] Tay KH(2001)XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor Cell 107 881-367