Consolidation chemotherapy during neoadjuvant chemoradiation (CRT) for distal rectal cancer leads to sustained decrease in tumor metabolism when compared to standard CRT regimen

[1] Sauer R(2012)Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years J Clin Oncol 30 1926-33

[2] Liersch T(2004)Preoperative versus postoperative chemoradiotherapy for rectal cancer N Engl J Med 351 1731-40

[3] Merkel S(2010)Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data Lancet Oncol 11 835-44

[4] Fietkau R(2008)Chemoradiotherapy for rectal cancer: an updated analysis of factors affecting pathological response Clin Oncol (R Coll Radiol) 20 176-83

[5] Hohenberger W(2010)Rectum-conserving surgery in the era of chemoradiotherapy Br J Surg 97 1752-64

[6] Hess C(2004)Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results Ann Surg 240 711-7

[7] Sauer R(2012)Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy Ann Surg 256 965-72

[8] Becker H(2011)Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer J Clin Oncol 29 4633-40

[9] Hohenberger W(2013)Watch and wait approach following extended neoadjuvant chemoradiation for distal rectal cancer: are we getting closer to anal cancer management? Dis Colon Rectum 56 1109-17

[10] Rodel C(2008)PET/CT and histopathologic response to preoperative chemoradiation therapy in locally advanced rectal cancer Dis Colon Rectum 51 21-5

[1] Sauer R(2012)Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years J Clin Oncol 30 1926-33

[2] Liersch T(2004)Preoperative versus postoperative chemoradiotherapy for rectal cancer N Engl J Med 351 1731-40

[3] Merkel S(2010)Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data Lancet Oncol 11 835-44

[4] Fietkau R(2008)Chemoradiotherapy for rectal cancer: an updated analysis of factors affecting pathological response Clin Oncol (R Coll Radiol) 20 176-83

[5] Hohenberger W(2010)Rectum-conserving surgery in the era of chemoradiotherapy Br J Surg 97 1752-64

[6] Hess C(2004)Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results Ann Surg 240 711-7

[7] Sauer R(2012)Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy Ann Surg 256 965-72

[8] Becker H(2011)Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer J Clin Oncol 29 4633-40

[9] Hohenberger W(2013)Watch and wait approach following extended neoadjuvant chemoradiation for distal rectal cancer: are we getting closer to anal cancer management? Dis Colon Rectum 56 1109-17

[10] Rodel C(2008)PET/CT and histopathologic response to preoperative chemoradiation therapy in locally advanced rectal cancer Dis Colon Rectum 51 21-5