The Health Utilities Index (HUI®): Concepts, measurement properties and applications

被引:1007
作者
John Horsman
William Furlong
David Feeny
George Torrance
机构
[1] Health Utilities Inc., Dundas, Ont.
[2] Dept. of Clin. Epidemiol./Biostat., McMaster University, Hamilton, Ont.
[3] Ctr. for Hlth. Econ./Policy Analysis, McMaster University, Hamilton, Ont.
[4] Institute of Health Economics, University of Alberta, Edmonton, Alta.
[5] Innovus Research Inc., Burlington, Ont.
关键词
Health status; Health Utilities Index; HRQL; HUI; HUI2; HUI3; Multi-attribute; QALYs; Quality of life; Review paper; Single-attribute; Utilities; Utility scores;
D O I
10.1186/1477-7525-1-54
中图分类号
学科分类号
摘要
This is a review of the Health Utilities Index (HUI®) multi-attribute health-status classification systems, and single- and multi-attribute utility scoring systems. HUI refers to both HUI Mark 2 (HUI2) and HUI Mark 3 (HUI3) instruments. The classification systems provide compact but comprehensive frameworks within which to describe health status. The multi-attribute utility functions provide all the information required to calculate single-summary scores of health-related quality of life (HRQL) for each health state defined by the classification systems. The use of HUI in clinical studies for a wide variety of conditions in a large number of countries is illustrated. HUI provides comprehensive, reliable, responsive and valid measures of health status and HRQL for subjects in clinical studies. Utility scores of overall HRQL for patients are also used in cost-utility and cost-effectiveness analyses. Population norm data are available from numerous large general population surveys. The widespread use of HUI facilitates the interpretation of results and permits comparisons of disease and treatment outcomes, and comparisons of long-term sequelae at the local, national and international levels. © 2003 Horsman et al; licensee BioMed Central Ltd.
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页数:13
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