Circulating magnesium as a potential risk stratification tool for sudden cardiac death: a systematic review; [Zirkulierendes Magnesium als potenzieller Risikostratifizierungsparameter für den plötzlichen Herztod – eine systematische Übersicht]

被引：0
作者：
Davis E. [1 ]
Fernando B.C. [1 ]
Jusni L.F.J. [1 ]
Hendryan K.R. [1 ]
Kuatama R. [1 ]
Ridjab D.A. [2 ]
机构：
[1] School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta
[2] Medical Education Unit, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Pluit Raya Rd. No. 2, North Jakarta
来源：
Herzschrittmachertherapie + Elektrophysiologie | 2023年 / 34卷 / 2期
关键词：
Left ventricular ejection fraction; Mortality; Normomagnesemia; Stratification strategy; Sudden cardiac death;
D O I：
10.1007/s00399-023-00941-8
中图分类号：
学科分类号：
摘要：
Background: Sudden cardiac death (SCD) is one of the main causes of cardiovascular mortality and accounts for 15–20% of deaths worldwide. The current stratification strategy using depressed left ventricular ejection fraction is insufficient to stratify the risk of SCD, especially in the general population. In recent years, there has been increasing evidence showing the antiarrhythmic properties of magnesium. In this systematic review, the authors aim to determine circulating magnesium as a potential risk stratification tool for SCD. Methods: This systematic review was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was conducted in July 2021 with sources from Google Scholar, PubMed, Science Direct, EBSCO Medline, and ProQuest. Results: A total of six studies were included in this review. Three studies conducted in the general population consistently showed lower risk of SCD in populations with high circulating magnesium. There was no association between circulating magnesium level and risk of SCD in intensive cardiac care unit (ICCU) patients, whilst the results were conflicting in congestive heart failure (CHF) patients. Conclusion: High circulating magnesium might have the potential to be utilized as a risk stratification tool for SCD, especially in the general population. However, further study is needed to support this evidence. © 2023, The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.
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页码：153 / 160
页数：7
相关论文
共 29 条
[1]  
Mozaffarian D., Benjamin E., Go A., Arnett D., Blaha M., Cushman M., Et al., Heart disease and stroke statistics—2015 update, Circulation, (2015)
[2]  
Hayashi M., Shimizu W., Albert C., The spectrum of epidemiology underlying sudden cardiac death, Circ Res, 116, 12, pp. 1887-1906, (2015)
[3]  
Wong C., Brown A., Lau D., Chugh S., Albert C., Kalman J., Et al., Epidemiology of sudden cardiac death: global and regional perspectives, Heart Lung Circ, 28, 1, pp. 6-14, (2019)
[4]  
Adabag A.S., Luepker R.V., Roger V.L., Gersh B.J., Sudden cardiac death: epidemiology and risk factors, Nat Rev Cardiol, 7, 4, pp. 216-225, (2010)
[5]  
Huikuri H., Prediction and prevention of sudden cardiac arrest, CMAJ, 183, 15, pp. 1692-1693, (2011)
[6]  
Fishman G., Chugh S., DiMarco J., Albert C., Anderson M., Bonow R., Et al., Sudden cardiac death prediction and prevention, Circulation, 122, 22, pp. 2335-2348, (2010)
[7]  
Fiorentini D., Cappadone C., Farruggia G., Prata C., Magnesium: biochemistry, nutrition, detection, and social impact of diseases linked to its deficiency, Nutrients, 13, 4, (2021)
[8]  
Jahnen-Dechent W., Ketteler M., Magnesium basics, Clin Kidney J, 5, 1, pp. i3-i14, (2012)
[9]  
DiNicolantonio J., Liu J., O'Keefe J., Magnesium for the prevention and treatment of cardiovascular disease, Open Heart, 5, 2, (2018)
[10]  
Tangvoraphonkchai K., Davenport A., Magnesium and cardiovascular disease, Adv Chronic Kidney Dis, 25, 3, pp. 251-260, (2018)
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