Spectrophotometry determination of metronidazole and tinidazole by their complexation with copper(II)

被引：0
作者：
O. I. Zheltvai
I. I. Zheltvai
V. V. Spinul
V. P. Antonovich
机构：
[1] National Academy of Sciences of Ukraine,Bogatsky Physico
来源：
Journal of Analytical Chemistry | 2013年 / 68卷
关键词：
photometry determination of nitroimidazoles; copper(II) complexes; control of tablet formulations; method certification;
D O I：
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学科分类号：
摘要：
It is shown that the treatment of chloroform solutions of drugs of the nitroimidazole series (NIm) with crystalline copper(II) acetate gives colored chloroform-soluble adducts of the general formula [Cu(CH3COO)2NIm]2, which can be used as analytical forms in the spectrophotometry determination of metronidazole and tinidazole. The respective analytical methods are developed and certified.
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页码：600 / 605
页数：5
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