Gene therapy of severe combined immunodeficiencies

被引：0
作者：
Alain Fischer
Salima Hacein-Bey
Marina Cavazzana-Calvo
机构：
[1] INSERM U429,
[2] Hôpital Necker,undefined
来源：
Nature Reviews Immunology | 2002年 / 2卷
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摘要：
The concept that the outcome of a devastating disease can be modified by inserting a transgene into abnormal cells is appealing. However, the gene-transfer technologies that are available at present have limited the success of gene therapy so far. Nevertheless, severe combined immunodeficiencies are a useful model, because gene transfer can confer a selective advantage to transduced cells. In this way, a proof of concept for gene therapy has been provided.
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页码：615 / 621
页数：6
相关论文
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