Metformin protects retinal pigment epithelium cells against H2O2-induced oxidative stress and inflammation via the Nrf2 signaling cascade

被引：0
|
作者：
Qiting Feng
Xiangcai Ruan
Min Lu
Shimiao Bu
Yuehong Zhang
机构：
[1] Zhongshan Ophthalmic Center,State Key Laboratory of Ophthalmology
[2] Sun Yat-Sen University,Department of Anesthesia and Pain Medicine
[3] Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Department of Ophthalmology
[4] The Sixth Affiliated Hospital,undefined
[5] Sun Yat-Sen University,undefined
[6] Sanshui Huaxia Eye Hospital,undefined
[7] Huaxia Eye Hospital Group,undefined
[8] Guangzhou First People’s Hospital,undefined
[9] School of Medicine,undefined
[10] South China University of Technology,undefined
来源：
Graefe's Archive for Clinical and Experimental Ophthalmology | 2024年 / 262卷
关键词：
Age-related macular degeneration; Metformin; Retinal pigment epithelial cells; Nrf2; Oxidative stress; Inflammation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1519 / 1530
页数：11
相关论文
共 50 条
  • [1] Metformin protects retinal pigment epithelium cells against H2O2-induced oxidative stress and inflammation via the Nrf2 signaling cascade
    Feng, Qiting
    Ruan, Xiangcai
    Lu, Min
    Bu, Shimiao
    Zhang, Yuehong
    GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2024, 262 (05) : 1519 - 1530
  • [2] Genipin protects against H2O2-induced oxidative damage in retinal pigment epithelial cells by promoting Nrf2 signaling
    Zhao, Hailan
    Wang, Ruiqing
    Ye, Mingxia
    Zhang, Lan
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 43 (02) : 936 - 944
  • [3] Exendin-4 Protects Human Retinal Pigment Epithelial Cells from H2O2-Induced Oxidative Damage via Activation of NRF2 Signaling
    Cui, Renzhe
    Tian, Lianji
    Lu, Di
    Li, Huiying
    Cui, Jun
    OPHTHALMIC RESEARCH, 2020, 63 (04) : 404 - 412
  • [4] Lycium barbarum polysaccharide protects ARPE-19 cells against H2O2-induced oxidative stress via the Nrf2/HO-1 pathway
    Liang, Ran
    Zhao, Qi
    Zhu, Qing
    He, Xin
    Gao, Mingjun
    Wang, Yiru
    MOLECULAR MEDICINE REPORTS, 2021, 24 (05)
  • [5] Neuroligin-3 protects retinal cells from H2O2-induced cell death via activation of Nrf2 signaling
    Li, Xiu-miao
    Huang, Dan
    Yu, Qing
    Yang, Jian
    Yao, Jin
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 502 (01) : 166 - 172
  • [6] Oxidative Stress Induces an Interactive Decline in Wnt and Nrf2 Signaling in Degenerating Retinal Pigment Epithelium
    Ebrahimi, Katayoon B.
    Cano, Marisol
    Rhee, John
    Datta, Sayantan
    Wang, Lei
    Handa, James T.
    ANTIOXIDANTS & REDOX SIGNALING, 2018, 29 (04) : 389 - 407
  • [7] Berberine protects immortalized line of human melanocytes from H2O2-induced oxidative stress via activation of Nrf2 and Mitf signaling pathway
    Jiang, Wei
    Li, Shuli
    Chen, Xuguang
    Zhang, Weigang
    Chang, Yuqian
    He, Yuanmin
    Zhang, Shaolong
    Su, Xin
    Gao, Tianwen
    Li, Chunying
    Jian, Zhe
    JOURNAL OF DERMATOLOGICAL SCIENCE, 2019, 94 (01) : 236 - 243
  • [8] Chitopentaose protects HaCaT cells against H2O2-induced oxidative damage through modulating MAPKs and Nrf2/ARE signaling pathways
    Zhang, Jing
    Wang, Wei
    Mao, Xiangzhao
    JOURNAL OF FUNCTIONAL FOODS, 2020, 72
  • [9] The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation
    Liu, Xiaobin
    Ward, Keith
    Xavier, Christy
    Jann, Jamieson
    Clark, Abbot F.
    Pang, Iok-Hou
    Wu, Hongli
    REDOX BIOLOGY, 2016, 8 : 98 - 109
  • [10] Triptonide protects retinal cells from oxidative damage via activation of Nrf2 signaling
    Li, Jinjing
    Li, Jiajun
    Cao, Yuan
    Yuan, Jin
    Shen, Yaming
    Lei, Linyi
    Li, Keran
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2024, 54 (03)
12345