Siah-1-interacting protein regulates mutated huntingtin protein aggregation in Huntington’s disease models

被引：0
|
作者：
Ewelina Latoszek
Małgorzata Wiweger
Jan Ludwiczak
Stanisław Dunin-Horkawicz
Jacek Kuznicki
Magdalena Czeredys
机构：
[1] International Institute of Molecular and Cell Biology in Warsaw,Structural Bioinformatics Laboratory, Centre of New Technologies
[2] Laboratory of Neurodegeneration,Laboratory of Bioinformatics
[3] University of Warsaw,undefined
[4] Nencki Institute of Experimental Biology,undefined
来源：
Cell & Bioscience | / 12卷
关键词：
Huntington’s disease; Huntingtin; Siah-1-interacting protein; Aggregation; Ubiquitination;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Arfaptin 2 regulates the aggregation of mutant huntingtin protein
    Peters, PJ
    Ning, K
    Palacios, F
    Boshans, RL
    Kazantsev, A
    Thompson, LM
    Woodman, B
    Bates, GP
    D'Souza-Schorey, C
    NATURE CELL BIOLOGY, 2002, 4 (03) : 240 - 245
  • [22] Arfaptin 2 regulates the aggregation of mutant huntingtin protein
    Peter J. Peters
    Ke Ning
    Felipe Palacios
    Rita L. Boshans
    Aleksey Kazantsev
    Leslie M. Thompson
    Ben Woodman
    Gillian P. Bates
    Crislyn D'Souza-Schorey
    Nature Cell Biology, 2002, 4 : 240 - 245
  • [23] Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models
    Sontag, Emily Mitchell
    Lotz, Gregor P.
    Agrawal, Namita
    Tran, Andrew
    Aron, Rebecca
    Yang, Guocheng
    Necula, Mihaela
    Lau, Alice
    Finkbeiner, Steven
    Glabe, Charles
    Marsh, J. Lawrence
    Muchowski, Paul J.
    Thompson, Leslie M.
    JOURNAL OF NEUROSCIENCE, 2012, 32 (32): : 11109 - 11119
  • [24] The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin
    Wang, Bo
    Zeng, Li
    Merillat, Sean A.
    Fischer, Svetlana
    Ochaba, Joseph
    Thompson, Leslie M.
    Barmada, Sami J.
    Scaglione, Kenneth M.
    Paulsona, Henry L.
    NEUROBIOLOGY OF DISEASE, 2018, 109 : 127 - 136
  • [25] A C-terminal ataxin-2 disordered region promotes Huntingtin protein aggregation and neurodegeneration in Drosophila models of Huntington's disease
    Huelsmeier, Joern
    Walker, Emily
    Bakthavachalu, Baskar
    Ramaswami, Mani
    G3-GENES GENOMES GENETICS, 2021, 11 (12):
  • [26] Reviewing Biochemical Implications of Normal and Mutated Huntingtin in Huntington's Disease
    Tellone, Ester
    Galtieri, Antonio
    Ficarra, Silvana
    CURRENT MEDICINAL CHEMISTRY, 2020, 27 (31) : 5137 - 5158
  • [27] Cdc42-interacting protein 4 binds to huntingtin:: Neuropathologic and biological evidence for a role in Huntington's disease
    Holbert, S
    Dedeoglu, A
    Humbert, S
    Saudlou, F
    Ferrante, RJ
    Néri, C
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (05) : 2712 - 2717
  • [28] TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models
    Hegde, Ramanath Narayana
    Chiki, Anass
    Petricca, Lara
    Martufi, Paola
    Arbez, Nicolas
    Mouchiroud, Laurent
    Auwerx, Johan
    Landles, Christian
    Bates, Gillian P.
    Singh-Bains, Malvindar K.
    Dragunow, Mike
    Curtis, Maurice A.
    Faull, Richard L. M.
    Ross, Christopher A.
    Caricasole, Andrea
    Lashuel, Hilal A.
    EMBO JOURNAL, 2020, 39 (17):
  • [29] Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein
    Sieradzan, KA
    Mechan, AO
    Jones, L
    Wanker, EE
    Nukina, N
    Mann, DMA
    EXPERIMENTAL NEUROLOGY, 1999, 156 (01) : 92 - 99
  • [30] HUNTINGTIN REGULATES CORTICAL DEVELOPMENT: CONSEQUENCES FOR HUNTINGTON'S DISEASE
    Barnat, Monia
    Humbert, Sandrine
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2016, 87 : A24 - A25
12345