Evaluation with contrast ultrasound of the prevalence of splenic infarction in left-sided infective endocarditis

被引：6

作者：

Menozzi G. ^{[1
]}

Maccabruni V. ^{[2
]}

Gabbi E. ^{[1
]}

Magnani G. ^{[1
]}

Garlassi E. ^{[1
]}

机构：

[1] Infectious Diseases Department, Azienda Ospedaliera S.Maria Nuova-IRCCS, Viale Risorgimento 80, Reggio Emilia

[2] Internal Medicine Department, San Sebastiano Hospital, Via Mandriolo Superiore 11, Correggio (Reggio Emilia)

来源：

Journal of Ultrasound | 2015年 / 18卷 / 3期

关键词：

Contrast; Embolization; Endocarditis; Spleen; Ultrasound;

D O I：

10.1007/s40477-014-0131-4

中图分类号：

学科分类号：

摘要：

Purpose: To prospectively evaluate the prevalence of the embolization of the spleen in patients with definite left-sided infective endocarditis (IE) using a contrast-enhanced ultrasound (CEUS). Methods: From March 2012 through September 2013, 18 consecutive patients (9 females and 9 males, aged 21–83 years) evaluated at our hospital and with definite left-sided IE according to the revised Duke criteria were enrolled. All of the patients gave informed written consent and the study was performed in conformity with the ethical guidelines of the Declaration of Helsinki. All of the patients were submitted to a CEUS of the spleen within 10 days after the definite diagnosis of IE. For the CEUS, a blood pool second-generation contrast agent and an ultrasound machine with a contrast harmonic imaging technology were used. Results: The splenic CEUS showed infarctions in 11 patients (61 %) and resulted positive in the 2 patients with negative echocardiography. Conclusions: In this study, CEUS of the spleen, a repeatable and low-cost imaging technique, easily allowed the bedside detection of asymptomatic and even tiny infarctions and showed a high rate of embolization in patients with definite left-sided IE. Therefore, in the setting of IE (possible or definite), CEUS of the spleen has the potential to better define or accelerate the diagnosis itself. © 2014, Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB).

引用

页码：223 / 227

页数：4

共 8 条

[1]

Fernandez Guerrero M.L., Alvarez B., Manzarbeitia F., Renedo G., Infective endocarditis at autopsy: a review of pathologic manifestations and clinical correlates, Medicine (Baltimore), 91, pp. 152-164, (2012)

[2]

Trouillet J.L., Hoen B., Battik R., Et al., Splenic involvement in infectious endocarditis. Association for the Study and Prevention of Infectious Endocarditis, Rev Med Interne, 20, pp. 258-263, (1999)

[3]

Ting W., Silverman N.A., Arzouman D.A., Levitsky S., Splenic septic emboli in endocarditis, Circulation, 82, 4, pp. 105-109, (1990)

[4]

Haft J.I., Altieri J., Smith L.G., Herskowitz M., Computed tomography of the abdomen in the diagnosis of splenic emboli, Arch Intern Med, 148, pp. 193-197, (1988)

[5]

Durack D.T., Lukes A.S., Bright D.K., New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service, Am J Med, 96, pp. 200-209, (1994)

[6]

Li J.S., Sexton D.J., Mick N., Et al., Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis, Clin Infect Dis, 30, pp. 633-638, (2000)

[7]

Menozzi G., Maccabruni V., Gabbi E., Leone N., Calzolari M., Contrast-Enhanced Ultrasound evaluation of splenic embolization in patients with definite left-sided infective endocarditis, Ultrasound Med Biol, 39, pp. 2205-2210, (2013)

[8]

Piscaglia F., Nolsoe C., Dietrich C.F., Et al., The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): update 2011 on non-hepatic applications, Ultraschall Med, 33, pp. 33-59, (2012)

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