Gold nanoparticles chemisorbed by a terphenyldithiol self-assembled monolayer for fabrication of a protein biosensor

被引：0
|
作者：
Nathir A. F. Al-Rawashdeh
W. Azzam
机构：
[1] United Arab Emirates University,Department of Chemistry
[2] Jordan University of Science & Technology,Department of Applied Chemical Sciences
[3] Tafila Technical University,Department of Chemistry
来源：
Research on Chemical Intermediates | 2011年 / 37卷
关键词：
Surface plasmon resonance; Terphenyldithiol; Self-assembled monolayers; Protein biosensor; Gold nanoparticles;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this study, improved detection of bovine serum albumin (BSA) was achieved by use of a fabricated surface plasmon resonance (SPR) biosensor. Terphenyldithiol (TPDT) was self-assembled on a gold substrate, then gold nanoparticles (Au-NPs) were chemisorbed on to the TPDT monolayer by strong bonding with the terminal thiol groups of the TPDT. The new sensor obtained was tested for immobilization of protein. The SPR results revealed much better detection of BSA by Au-NPs chemisorbed on the TPDT self-assembled monolayer (SAM) than by the bare SAM on the gold substrate.
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页码：759 / 770
页数：11
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