Peculiarities of Determining Bacterial Endotoxins in Oil Solutions of Drugs

被引:0
作者
O. V. Shapovalova
N. P. Neugodova
G. A. Sapozhnikova
机构
[1] Ministry of Health of the Russian Federation,Scientific Center for Expert Evaluation of Medicinal Products
来源
Pharmaceutical Chemistry Journal | 2020年 / 54卷
关键词
bacterial endotoxins; extraction; oil solutions; dispersing solvent;
D O I
暂无
中图分类号
学科分类号
摘要
Issues related to reliable quality assessment of oil solutions of medicines with respect to the Bacterial Endotoxins indicator are considered. The maximum isolation of bacterial endotoxins from fat-soluble drugs for subsequent determination is assisted by vigorous stirring of samples in water previously heated to 60°C followed by separation of the two phases using centrifugation at 2300 rpm for 10 min.
引用
收藏
页码:539 / 543
页数:4
相关论文
empty
未找到相关数据