Influenza and HIV: Lessons from the 2009 H1N1 influenza pandemic

被引：33
作者：
Sheth A.N. [1 ,3 ]
Patel P. [2 ]
Peters P.J. [2 ]
机构：
[1] Department of Medicine, Emory University School of Medicine, Atlanta, GA
[2] Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA
[3] Atlanta, GA 30303
来源：
Current HIV/AIDS Reports | 2011年 / 8卷 / 3期
关键词：
Complications of HIV infection and treatment; Epidemiology; H1N1; Human immunodeficiency virus; Influenza; Pandemic;
D O I：
10.1007/s11904-011-0086-4
中图分类号：
学科分类号：
摘要：
Influenza is a common respiratory disease in adults, including those infected with HIV. In the spring of 2009, a pandemic influenza A (H1N1) virus (pH1N1) emerged. In this article, we review the existing literature regarding pH1N1 virus infection in HIV-infected adults, which suggests that susceptibility to pH1N1 virus infection and severity of influenza illness are likely not increased in HIV-infected adults without advanced immunosuppression or comorbid conditions. The risk of influenza-related complications, however, may be increased in those with advanced immunosuppression or high-risk comorbid conditions. Prevention and treatment of high-risk comorbid conditions and annual influenza vaccination should continue to be part of HIV clinical care to help prevent influenza illness and complications. Additional information about pH1N1 vaccine immunogenicity and efficacy in HIV-infected patients would be useful to guide strategies to prevent influenza virus infection in this population. © Springer Science+Business Media, LLC 2011.
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页码：181 / 191
页数：10
相关论文
共 91 条
[81]  
Evison J., Farese S., Seitz M., Uehlinger D.E., Furrer H., Muhlemann K., Randomized, double-blind comparative trial of subunit and virosomal influenza vaccines for immunocompromised patients, Clin Infect Dis, 48, 10, pp. 1402-1412, (2009)
[82]  
Tebas P., Frank I., Lewis M., Et al., Poor immunogenicity of the H1N1 2009 vaccine in well controlled HIV-infected individuals, AIDS, 24, 14, pp. 2187-2192, (2010)
[83]  
Yamanaka H., Teruya K., Tanaka M., Kikuchi Y., Takahashi T., Kimura S., Oka S., Efficacy and immunologic responses to influenza vaccine in HIV-1-infected patients, Journal of Acquired Immune Deficiency Syndromes, 39, 2, pp. 167-173, (2005)
[84]  
Atashili J., Kalilani L., Adimora A.A., Efficacy and clinical effectiveness of influenza vaccines in HIV-infected individuals: A meta-analysis, BMC Infect Dis, 6, (2006)
[85]  
Bickel M., Wieters I., Khaykin P., Et al., Low rate of seroconversion after vaccination with a split virion, adjuvanted pandemic H1N1 influenza vaccine in HIV-1-infected patients, AIDS, 24, 9, (2010)
[86]  
Bickel M., Von Hentig N., Wieters I., Et al., Immune response after two doses of the novel split virion, adjuvanted pandemic H1N1 influenza A vaccine in HIV-1-infected patients, Clin Infect Dis., 52, 1, pp. 122-127, (2011)
[87]  
Durier C., Desaint C., Colin De Verdiere N., Et al., Durability of immune response after vaccination with 2 doses of influenza A H1N1v 2009 vaccine formulated with and without AS03Aadjuvant in HIV+ adults: ANRS 151 randomized HIFLUVAC trial, 18th Conference on Retroviruses and Opportunistic Infections, (2011)
[88]  
Orlando G., Pariani E., Mazza F., Et al., Pandemic influenza vaccine in adult HIV-1-infected patients, AIDS, 24, 13, pp. 2142-2143, (2010)
[89]  
Soonawala D., Rimmelzwaan G.F., Gelinck L.B., Visser L.G., Kroon F.P., Response to 2009 pandemic influenza A (H1N1) vaccine in HIV-infected patients and the influence of prior seasonal influenza vaccination, PLoS One, 6, 1, (2011)
[90]  
Cooper C., Klein M., Walmsley S., Hasse D., Scheifele D., Network PHAoC-CIoHRIR. A randomized trial to compare the immunogenicity and efficacy of adjuvanted pandemic H1N12009 vaccine with or without booster in HIV+ adults, 18th Conference on Retroviruses and Opportunistic Infections, (2011)
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